Protein Alignment CG6125 and SLC26A3

DIOPT Version :10

• Sequence 1: NP_732032.1
• Gene: CG6125 / 41882
• FlyBaseID: FBgn0038337
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_000102.1
• Gene: SLC26A3 / 1811
• HGNCID: 3018
• Length: 764
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 145/574 - (25%)
• Similarity: 259/574 - (45%)
• Gaps: 105/574 - (18%)

  Fly    43 EEKEKYTAQNGDDYYGQAHTVDLD---VASKYSKPKEAHWLVRRIF-FLSWITSYD-REQAFADL 102
            ||..|.|        |:.|...||   |....| |::|..:|..:| ..||:.:|. :|...:|:
Human    22 EENHKKT--------GRHHKTFLDHLKVCCSCS-PQKAKRIVLSLFPIASWLPAYRLKEWLLSDI 77

  Fly   103 IAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFFGTIPQVSIGPTSLMAIL------ 161
            ::||:.|:..:.|.:|:|.|..:...||||::|..:|||:||||...:|:||..:::::
Human    78 VSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVS 142

  Fly   162 -------------TL---------QFCADKPVQVVIV--LAFLAGLVELAMGVFQLGFIVSFIPA 202
                         ||         ....|:.|:|...  :..|:|:::||.|:.::||:|.::..
Human   143 GAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSE 207

  Fly   203 PVTKAFTSGTALIVVFAQIKNLLGVRIKG-------FPSIGDFFTNIRPTDAAMGISCMVVLLSL 260
            .:...||:..|:.|:.:|:|.:..:.:..       |..:...|:.|..|:.|..::.::|||.:
Human   208 SLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVV 272

  Fly   261 RLLSQVN--FKQDTPVTRRLKKILWYISISRNALVVFFTGLLVFIWVKKSSIEAVPFALSSKVSS 323
            .::.::|  ||...||...::.|:..|:...:....|.....|.:                 |..
Human   273 SIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAV-----------------VGD 320

  Fly   324 AMPTIKLP--PFAFEYQNRTYVFTDILHELGS--GIVVVPIVAVLANVAIAKAFVKDGNLDASQE 384
            ..|..:.|  |....:||          .:|.  ||.:|.. ||..:||...:...|..||.:||
Human   321 MNPGFQPPITPDVETFQN----------TVGDCFGIAMVAF-AVAFSVASVYSLKYDYPLDGNQE 374

  Fly   385 MLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYIP--K 447
            ::.|||.||....|.......|.:||||.:::|.:|.:||:...:|||  :.:|...|...|  |
Human   375 LIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVL--IVVLAIGFLLAPLQK 437

  Fly   448 ASLSAVLIAAVIFMI-DLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILLR 511
            :.|:|:.:..:..|: ..|.:..||:.:|.|...|:.:||..:|.|:.|||...:...::.|:.|
Human   438 SVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFR 502

  Fly   512 LGNPKF-------EVTLKQHESTYYVHIVPQ--------SDVYYTGVDALRSEL 550
            ...||.       ...:.:::..||....|:        |.:|:..:...|.:|
Human   503 TQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	PRK11660	87..620	CDD:481320	131/526 (25%)
SLC26A3	NP_000102.1	Sulfate_transp	73..475	CDD:459995	109/431 (25%)
		STAS_SulP_like_sulfate_transporter	526..712	CDD:132913	7/31 (23%)
		PDZ-binding. /evidence=ECO:0000269|PubMed:22627094	761..764