Protein Alignment CG6125 and SLC26A1

DIOPT Version :9

• Sequence 1: NP_732032.1
• Gene: CG6125 / 41882
• FlyBaseID: FBgn0038337
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_071325.2
• Gene: SLC26A1 / 10861
• HGNCID: 10993
• Length: 701
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 151/637 - (23%)
• Similarity: 267/637 - (41%)
• Gaps: 155/637 - (24%)

  Fly    89 WITSY-DREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFFGTIPQVSI 152
            |:..| .||....|:::|:.:|:.::||:|||:.||||...|.||::|..::||...||...||:
Human    59 WLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSV 123

  Fly   153 GPTSLMAILT-------LQFCADKP-----------------------------VQVVIVLAFLA 181
            |..||:.::.       ||.....|                             ::|...|..:.
Human   124 GIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVATALTLMT 188

  Fly   182 GLVELAMGVFQLGFIVSFIPAPVTKAFTSGTALIVVFAQIKNLLGVRIKGFPSIG----DFFTNI 242
            ||.::.|||.:|||:.:::..|:...|..|.::.::.:|:|:||||||......|    .:.:.:
Human   189 GLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLL 253

  Fly   243 RPT------DAAMGISCMVVLLSLRLLSQVNFKQDTPVTRRLKKILWYISISRNALVVFFTGLLV 301
            |..      |......|:.|||:.:.||.       ....||:     :.:....||:....|:
Human   254 RGAGQANVCDVVTSTVCLAVLLAAKELSD-------RYRHRLR-----VPLPTELLVIVVATLV- 305

  Fly   302 FIWVKKSSIEAVPFALSSKVSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVVPIVAVLAN 366
                  |....:.....|.|:..:||..:||...|.:        ::..:....|.:.:||...:
Human   306 ------SHFGQLHKRFGSSVAGDIPTGFMPPQVPEPR--------LMQRVALDAVALALVAAAFS 356

  Fly   367 VAIAKAFVKDG--NLDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGL 429
            :::|:.|.:..  ::.|:||:|.:|.||:..:|.....|..|..:|.|..|:|.||.::.:.:..
Human   357 ISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSAT 421

  Fly   430 IVLSALSILTPYFQYIPKASLSAVLI----AAVIFMIDLAPVKELWQTNKKDFFSWVGSFIICLV 490
            :||..|..|.|.|..:.::.|:.|::    .|:..:.||   ..||:.:..|...|.|:...|::
Human   422 VVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDL---PRLWRMSPADALVWAGTAATCML 483

  Fly   491 AGVELGLLFGIVLSMV-----------FILLRLGNPKFEVTLKQHESTYYVHIVPQSDV------ 538
            ...|.|||.|::||::           .:|.|:|:..|     ..::|.:..:||:..|
Human   484 VSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAF-----YEDATEFEGLVPEPGVRVFRFG 543

  Fly   539 ---YY-------------TGVDA-------------------------------LRSELRGACRL 556
               ||             ||:||                               .|:.|..|...
Human   544 GPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAG 608

  Fly   557 YHNDFPVVLDCARFMQFDATFSEMLISVAKEMASHDVLLILQNMSLKVQQML 608
            :|.   ||:|||..:..||.....|..:.::..:..:.|:|...|..|:.:|
Human   609 FHT---VVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDIL 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	151/637 (24%)
		HCO3_cotransp	108..462	CDD:304903	99/405 (24%)
		STAS	530..608	CDD:294402	25/130 (19%)
SLC26A1	NP_071325.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		sulP	55..683	CDD:273284	151/637 (24%)
		STAS_SulP_like_sulfate_transporter	528..669	CDD:132913	26/133 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810