DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6125 and slc26a11

DIOPT Version :9

Sequence 1:	NP_732032.1	Gene:	CG6125 / 41882	FlyBaseID:	FBgn0038337	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_002937354.2	Gene:	slc26a11 / 100486579	XenbaseID:	XB-GENE-955145	Length:	594	Species:	Xenopus tropicalis

Alignment Length:	560	Identity:	188/560 - (33%)
Similarity:	309/560 - (55%)	Gaps:	53/560 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LVRRIFFLSWITSYDREQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFF 144
            |.:|:.||.|:..|..:....|:|||||:|||::||::|||.:|||..::||||:|:|..||.|.
Frog    26 LQKRLPFLQWLPRYSLQWLQLDIIAGITVGLTVVPQALAYAEVAGLPVQFGLYSSFVGCFIYCFL 90

  Fly   145 GTIPQVSIGPTSLMAILTLQFCADKPVQVVIVLAFLAGLVELAMGVFQLGFIVSFIPAPVTKAFT 209
            ||...|::|||::|::|...:... .:.:.|:|.|::|.::||||:...||::.||..||.||||
Frog    91 GTSKDVTLGPTAIMSLLVFVYTLG-DLSLAILLTFISGCIQLAMGLLNFGFLLDFISYPVIKAFT 154

  Fly   210 SGTALIVVFAQIKNLLGVR-------------IKGFPSIGDFFTNIRPTDAAMGISCMVVLLSLR 261
            |..|:.:.|:|:|||||::             .:..||       .||.||.:||.|:.:||:|:
Frog   155 SAAAITIAFSQVKNLLGLQDIPRQFILQVYQTFRKLPS-------TRPGDAILGILCIAILLALK 212

  Fly   262 LLSQVNFK--QDTPVTRRL-KKILWYISISRNALVVFFTGLLVFIWVKKSSIEAV---PFALSSK 320
            .:.....:  |...:..|: ..|:|.::.:||||:|...||:.:      |...:   ||.|:.|
Frog   213 WMKDHTSRPYQGMSICHRICYLIVWIMTTARNALIVVGAGLVAY------SFHVMGLHPFILTGK 271

  Fly   321 VSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVVPIVAVLANVAIAKAFVKDGN--LDASQ 383
            .:..:|..:||||:....|.|..|::::..:||||:::|::.:|.:||||:||....|  :..:|
Frog   272 TAKGLPQFQLPPFSEITPNGTKTFSEMVQVIGSGILIIPLMGLLESVAIARAFASQNNYRIKTNQ 336

  Fly   384 EMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILTPYFQYIPKA 448
            |:|.:||.||.|||.|:.|..|:|.|:|::..:||.||..||.|||:||.:|..|||.|.:||||
Frog   337 ELLAIGLTNILGSFLSSYPVTGSFGRTALNSQTGVCTPAGGIITGLLVLLSLGYLTPAFYFIPKA 401

  Fly   449 SLSAVLIAAVIFMIDLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVLSMVFILLRLG 513
            :|:||:|.||..|.||...|.:|:..:.|...:..:|::.... ::.|:|.|..:|::|:...:.
Frog   402 ALAAVIICAVAPMFDLRICKSMWKVKRLDLIPFFVTFLLSFWE-IQYGILAGTFVSIIFLCYPIA 465

  Fly   514 NPKFEVTLKQHESTYYVHIVPQSDVYYTGVDALRSELRGACRLYHNDF------PVVLDCARFMQ 572
            .|:.:|:     ....:.:.|.|.:.:..::.|:.      ::|...|      .|.||......
Frog   466 RPEIKVS-----DMDGLILTPMSGLSFPAMEYLKD------KIYEKTFTVSSPQSVTLDFTHVTA 519

  Fly   573 FDATFSEMLISVAKEMASHDVLLILQNMSLKVQQMLPVMG 612
            .|.|....|..:..|..:..|.|....:...:..|....|
Frog   520 IDYTVVVGLAELLSEFKAQGVCLTFSGLQPPLLHMFSSSG 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	185/553 (33%)
		HCO3_cotransp	108..462	CDD:304903	146/374 (39%)
		STAS	530..608	CDD:294402	14/83 (17%)
slc26a11	XP_002937354.2	sulP	31..563	CDD:273284	186/555 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11814
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110