DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6125 and slc26a10

DIOPT Version :9

Sequence 1:	NP_732032.1	Gene:	CG6125 / 41882	FlyBaseID:	FBgn0038337	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_001921766.4	Gene:	slc26a10 / 100150270	ZFINID:	ZDB-GENE-030131-9845	Length:	690	Species:	Danio rerio

Alignment Length:	721	Identity:	168/721 - (23%)
Similarity:	312/721 - (43%)	Gaps:	160/721 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ATVATIYDPGCEEKEKYTAQNGDDYYGQAHTVD-LDVASKYSKPKEAHWLVRRIFFLSWITSYD- 94
            |:||...:...|::.:.|....|...|:....| |......|:.:..|.|.:|:...||:..|.
Zfish     3 ASVAIYRNIYTEDRFRQTYGTEDQSGGRERLRDRLAQRCSCSQVECVHLLHKRLPVCSWLPKYKL 67

  Fly    95 REQAFADLIAGITLGLTIIPQSIAYAALAGLSSEYGLYSAFIGSIIYVFFGTIPQVSIGPTSLMA 159
            |:....|:|||:|:|:..|||.:|:|.|..::..||||::|...::|:.|||...||.|..::::
Zfish    68 RKWLLGDIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTGHHVSTGTFAVLS 132

  Fly   160 ILT---------------------LQFCADKPVQVVIVLAFLAGLVELAMGVFQLGFIVSFIPAP 203
            ::|                     .:|.|.: :.|...:|||:|::.|.|...||||:.:::..|
Zfish   133 LMTGSVVEQLVPIPLALNSSSPEAAEFEAQR-IGVASAVAFLSGIMMLCMCGLQLGFLSTYLSEP 196

  Fly   204 VTKAFTSGTALIVVFAQIKNLLGVRIKG-------FPSIGDFFTNIRPTDAA---MGISCMVVLL 258
            :.|||||..|..|..:|::::||:|:..       |.::.....|:..|:.|   :.:.|:.||:
Zfish   197 IVKAFTSAAAFHVTVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNLAELVISLLCLAVLV 261

  Fly   259 SLRLLSQVN--FKQ--DTPVTRRLKKILWYISISRNALVVFFTGLLVFIWVKKSSIEAVPFALSS 319
            .::   :||  |::  .||:...:            ..|:..||:            ...|:|.|
Zfish   262 PVK---EVNSRFRERLRTPIPVEI------------ITVIIATGI------------TYAFSLDS 299

  Fly   320 K--------VSSAMPTIKLPPFAFEYQNRTYVFTDILHELGSGIVVVPIVAVLANVAIAKAFV-K 375
            |        :.:..|..:||..            :.:.|:....|.:.:||...:|::|..:. |
Zfish   300 KYDIQIVGHIPAGFPEPRLPAL------------ETVPEIAGDTVAITLVAYAVSVSLAMIYADK 352

  Fly   376 DG-NLDASQEMLTLGLCNIAGSFFSAMPTCGAFTRSAVSQASGVRTPMAGIYTGLIVLSALSILT 439
            .| ::|.:||:|..|:.|...|.|:..|.......:.:.:::|..|.:||::|.|:||..|.::.
Zfish   353 HGYSIDPNQELLAHGISNTVSSLFTCFPNSATLATTNILESAGGHTQLAGLFTSLVVLIVLLLIG 417

  Fly   440 PYFQYIPKASLSAVLIAAVIFM-IDLAPVKELWQTNKKDFFSWVGSFIICLVAGVELGLLFGIVL 503
            |.|.::|||.|:.:.:.::..| :....:.|||:.:|.||..|:.:::..:|..|:|||..|:|.
Zfish   418 PLFYFLPKAVLACINVTSLRQMFLQFQDLPELWRISKIDFMVWLVTWLSVVVLNVDLGLAIGMVF 482

  Fly   504 SMVFILLR--------LG---NPKFEVTLKQHESTYYVH----IVPQSDVYY------------- 540
            ||:.::.|        ||   |.:...::..|...|.|.    :.....:||
Zfish   483 SMMTVVCRTQRASCSVLGRAANTEIYRSINNHNKCYEVPGVKILTYNGPIYYGNRSFFKADMAQL 547

  Fly   541 ------------TGVDALRSELRGACRLYH-----------NDF-----------PVVLDCARFM 571
                        ..:.|:....|.|.....           ||.           .|::||:..:
Zfish   548 LGLTPERIRSREKALKAIEKREREAISTVEQGVADSSFSSKNDLFTSEMAEGEVQAVLIDCSSVI 612

  Fly   572 QFDATFSEMLISVAKEMASHDVLLILQNMSLKVQQMLPVMGNVRFCQ--------EDSQLSSHLQ 628
            ..|...:.:.|.:..|.....|.:.|.|.:..|.::|...|.:.:..        .|:.:  ::|
Zfish   613 FVDIAGARLFIQMCMECQKIGVRIYLANCNESVLKILTSSGLMNYMNPQHIFVTIHDAVV--YIQ 675

  Fly   629 VEKEAP 634
            .::|.|
Zfish   676 QQREKP 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6125	NP_732032.1	sulP	87..620	CDD:273284	151/649 (23%)
		HCO3_cotransp	108..462	CDD:304903	100/399 (25%)
		STAS	530..608	CDD:294402	18/128 (14%)
slc26a10	XP_001921766.4	Sulfate_transp	57..670	CDD:332851	151/652 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810