DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp and RUD3

DIOPT Version :9

Sequence 1:	NP_001189227.1	Gene:	Rbp / 41880	FlyBaseID:	FBgn0262483	Length:	1844	Species:	Drosophila melanogaster
Sequence 2:	NP_014859.3	Gene:	RUD3 / 854391	SGDID:	S000005742	Length:	484	Species:	Saccharomyces cerevisiae

Alignment Length:	145	Identity:	29/145 - (20%)
Similarity:	60/145 - (41%)	Gaps:	28/145 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 QKHKQQKSRPRGSHSMPYESMHHHQSAAAAVAAGTTPNGMLDALSLQLRDAEMRRTEIERAHQET 93
            :.:||..|..|.......:::..|:...|.:      ...|:.|.|::.:.:.:|.|..|...:.
Yeast   265 ENNKQDISDLRTERDELRQALESHEKEKAVL------KNSLNDLELKIEEVDNKREEEARERDQE 323

  Fly    94 LAQIRNLSGSA----RPDAEAVENLQSRARELEKKVALENVRCEE-----LQI------------ 137
            :..:|:...:.    ..|.||:|:::.:...:::..:::....||     |||
Yeast   324 VKSLRSQLDTEIETHNNDTEALESMKKQLEAMKEDASMKEKYEEESKQHILQIGKLRHEAIILNE 388

  Fly   138 ELTSAL-KAKQASRS 151
            .||.|| ..|::|.|
Yeast   389 HLTKALAMLKKSSDS 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp	NP_001189227.1	SH3	609..677	CDD:302595
		FN3	748..822	CDD:238020
		FN3	844..907	CDD:238020
		SH3_RIM-BP_2	1319..1380	CDD:212945
		SH3_RIM-BP_3	1446..1507	CDD:212946
RUD3	NP_014859.3	SMC_prok_A	88..>382	CDD:274009	22/122 (18%)
RUD3	NP_014859.3	GRAB	401..449	CDD:402134	2/3 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5407
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030