DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp and pqn-63

DIOPT Version :9

Sequence 1:	NP_001189227.1	Gene:	Rbp / 41880	FlyBaseID:	FBgn0262483	Length:	1844	Species:	Drosophila melanogaster
Sequence 2:	NP_505479.3	Gene:	pqn-63 / 188181	WormBaseID:	WBGene00004146	Length:	469	Species:	Caenorhabditis elegans

Alignment Length:	452	Identity:	134/452 - (29%)
Similarity:	163/452 - (36%)	Gaps:	102/452 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   916 AAN---VGQTGGAGRPGQEEAPGAYADFRTLTKGLPDPPQEIQLEAGPQDGTILVTWQPVNRPTS 977
            |||   .|....|..|....|||...:     :.||.||.|   :..|||.::    |....|..
Worm    53 AANPLAPGPVAPAPGPAPGPAPGPAPE-----ENLPTPPPE---QYPPQDYSV----QSPPAPQG 105

  Fly   978 TGPVTGYAVYADGKKVTDINSPTGDHALIDIGKLGVFNPRAVTIRTKSRDSQSADSAPILIPNTV 1042
            ..|     :|..|:      :|.|..|           .|.|   ...:..|:....|...||..
Worm   106 QQP-----IYPGGQ------TPQGYPA-----------HRPV---YPQQPLQNPQGYPQGYPNAA 145

  Fly  1043 RNAVARRGPNQMGMGPQLPQGPHGMTVQQQMGGMPGQPGQ--QG--QHMMGGQQDHGQYDPNQMQ 1103
            ::.....|..|.......||.|.   .||...|.|| |.|  ||  |:....|...|.    ...
Worm   146 QSPSQPPGYPQQQASQGYPQPPQ---AQQTPQGYPG-PAQIPQGYPQNQQAPQMSQGY----SQA 202

  Fly  1104 QQQQQQGQPGQPGHQPDAGSGLLGGLLGGLFSKPTQNQVNQNGYQPG-QPGAQRGMVPIPGRPQG 1167
            .||..||.|..| .||         |:.|.: .|:|.:  ..||..| |..||        .|||
Worm   203 SQQAPQGHPSGP-QQP---------LMTGQY-PPSQQK--PQGYTQGYQDSAQ--------VPQG 246

  Fly  1168 PQQQQQQPYGPQG-PMGGPRFRGPVPGQLNMQGQQMQGQMQGQMQGQMQGQMSGQMPGQMPGQMP 1231
            ..|.||.|..||| |...|:    .|.|.....||.|.......| |:|.|.|...|...|.|.|
Worm   247 YPQSQQAPQAPQGYPQQPPQ----DPTQYAQPPQQQQPYPYPSQQ-QLQSQASQGYPQNYPQQQP 306

  Fly  1232 GQMPGQMAGQMAGQM--PGQMPGQMPGQMSGQMPGQMMGPRGPLNQQQQQQQQMQQGQMMPGQQA 1294
              ||.|.:.|.|.|.  |.|.|.|.||.:..|.|.|.  |:||..||....||..|| :....|.
Worm   307 --MPSQYSPQQAQQQLPPSQYPEQGPGPIQQQFPQQY--PQGPAQQQAPGPQQYPQG-LQGSPQG 366

  Fly  1295 GQQQAQPGQPGQPGQMPGAQKKPRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDK 1356
            .|||..|.||.|  |||...:            |..:....|...|......|:.:: |||:
Worm   367 SQQQQMPPQPQQ--QMPSYNQ------------PEALRQEIDQIQEGPMPTRGNRLQ-FGDE 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp	NP_001189227.1	SH3	609..677	CDD:302595
		FN3	748..822	CDD:238020
		FN3	844..907	CDD:238020
		SH3_RIM-BP_2	1319..1380	CDD:212945	7/38 (18%)
		SH3_RIM-BP_3	1446..1507	CDD:212946
pqn-63	NP_505479.3	PABP-1234	<93..229	CDD:130689	45/183 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3632
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900