Protein Alignment h-cup and SIKE1

DIOPT Version :9

• Sequence 1: NP_650462.1
• Gene: h-cup / 41879
• FlyBaseID: FBgn0038334
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001095866.1
• Gene: SIKE1 / 80143
• HGNCID: 26119
• Length: 211
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 56/224 - (25%)
• Similarity: 88/224 - (39%)
• Gaps: 74/224 - (33%)

  Fly    32 DELLIDAK---------------MVDQELANCHK----FRE------DQLLKHLTEKNDDDEQM- 70
            :::|.|||               :|||..| .|:    .||      ||:.:...|...|.:.|
Human     6 EKILTDAKTLLERLREHDAAAESLVDQSAA-LHRRVAAMREAGTALPDQVRQRYQEDASDMKDMS 69

  Fly    71 ----------------QLLRENIELKATGVEFQHGIELIMEKYREHS----------EGDMLIDT 109
                            .|.:||.||..:..|.|..:||||.|||:..          :.:.::..
Human    70 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKA 134

  Fly   110 YQLREHYLAGLSKVVEEQDARIERMVDVMKLTVDFEDRSSAENQQIICQLTDENEQLRRQLQIST 174
            :|  .|     |..:|.|..||..|.:||:..|..:|....:.|:.:.||..||::||..|.||:
Human   135 HQ--SH-----SAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISS 192

  Fly   175 TDELFRQGALSSSESSTQIGPNDSLDSSA 203
                          .|.|....:|:|:::
Human   193 --------------ESLQARKENSMDTAS 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
h-cup	NP_650462.1	DUF837	12..173	CDD:283437	50/192 (26%)
SIKE1	NP_001095866.1	DUF837	2..191	CDD:310401	50/192 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003688
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12186
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	3.060