Protein Alignment h-cup and FGFR1OP2

DIOPT Version :9

• Sequence 1: NP_650462.1
• Gene: h-cup / 41879
• FlyBaseID: FBgn0038334
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_056448.1
• Gene: FGFR1OP2 / 26127
• HGNCID: 23098
• Length: 253
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 54/234 - (23%)
• Similarity: 97/234 - (41%)
• Gaps: 52/234 - (22%)

  Fly    14 IKEYKDFAKCLDELEFKTDELLIDAKMVDQELANCHKFREDQ----LLKHLTEKNDDDEQMQLLR 74
            ::::.|.|:.|.|.....::.:...|...:|:...::....:    |:..:.::|....::|  :
Human    19 LRDHDDAAESLIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQ--Q 81

  Fly    75 ENIELKATGVEFQHGIELIMEKYRE-----------------------HSEGDML---------I 107
            ||.||:.:..|.|..:||||.||||                       ||:.||:         :
Human    82 ENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFL 146

  Fly   108 DT---------YQLREHYLAGLSKVVEEQDARIERMVDVMKLTVDFEDRSSAENQQIICQLTDEN 163
            |.         :.|...:|......::....:|..|..||:..::.:::...:.|:.|.||..||
Human   147 DASRHILEAPQHGLERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQEN 211

  Fly   164 EQLRRQLQISTTDELF---RQGALSSSESSTQIGPNDSL 199
            :.||..|||  |.|.|   |:...|.|.|.:.:..|..|
Human   212 KGLREILQI--TRESFLNLRKDDASESTSLSALVTNSDL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
h-cup	NP_650462.1	DUF837	12..173	CDD:283437	44/203 (22%)
FGFR1OP2	NP_056448.1	SIKE	2..221	CDD:399056	45/205 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	231..253		5/18 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003688
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12186
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	3.060