Protein Alignment CG6136 and CUTC

DIOPT Version :9

• Sequence 1: NP_001189224.1
• Gene: CG6136 / 41877
• FlyBaseID: FBgn0038332
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_057044.2
• Gene: CUTC / 51076
• HGNCID: 24271
• Length: 273
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 104/252 - (41%)
• Similarity: 144/252 - (57%)
• Gaps: 15/252 - (5%)

  Fly    12 LEVCVDSIRSAFAAEEGGASRIELCSALGEGGLTPSIGTLKTIKETLTMPIYCMLRPRRGTDFVY 76
            :||||||:.||..||.|||.||||||.|.|||.|||:|.|:.:|:::.:|::.|:|| ||.||:|
Human    28 MEVCVDSVESAVNAERGGADRIELCSGLSEGGTTPSMGVLQVVKQSVQIPVFVMIRP-RGGDFLY 91

  Fly    77 SDEEMCALLTDMDLLRENGADGFVFGSLNPDRSINVDQCRHVLLASGGLPVTFHRAFDLTDQKSM 141
            ||.|:..:..|:.|.:..||||.|||:|..|..|:.:.|..::.....||||||||||:.....
Human    92 SDREIEVMKADIRLAKLYGADGLVFGALTEDGHIDKELCMSLMAICRPLPVTFHRAFDMVHDPM- 155

  Fly   142 DENVDMLRELGFRRLLSSGFRPTAADGVDCLAQLIAKHQRDFIVMPGAGIKVSNLEEILTVSRCL 206
             ..::.|..|||.|:|:||...:|.:|:..:.:||.:.:...:||||.||...||:.||..|...
Human   156 -AALETLLTLGFERVLTSGCDSSALEGLPLIKRLIEQAKGRIVVMPGGGITDRNLQRILEGSGAT 219

  Fly   207 EFHASALDT--AGEDYVAPTTTRMECDVTMGKQDVDPYYG---TNSIVVRKMVTIAK 258
            |||.||..|  :|..:       ....|.||.......|.   |:...||.:..|||
Human   220 EFHCSARSTRDSGMKF-------RNSSVAMGASLSCSEYSLKVTDVTKVRTLNAIAK 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6136	NP_001189224.1	CutC	10..259	CDD:225684	104/252 (41%)
CUTC	NP_057044.2	CutC	27..269	CDD:225684	102/250 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160412
Domainoid	1	1.000	173	1.000	Domainoid score	I3717
eggNOG	1	0.900	-	-		E1_COG3142
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9318
Inparanoid	1	1.050	174	1.000	Inparanoid score	I4077
Isobase	1	0.950	-	0	Normalized mean entropy	S4196
OMA	1	1.010	-	-		QHG62661
OrthoDB	1	1.010	-	-		D1619869at2759
OrthoFinder	1	1.000	-	-		FOG0006124
OrthoInspector	1	1.000	-	-		oto89979
orthoMCL	1	0.900	-	-		OOG6_104810
Panther	1	1.100	-	-	LDO	PTHR12598
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2469
SonicParanoid	1	1.000	-	-		X4415
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750