DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34404 and Ushbp1

DIOPT Version :9

Sequence 1:	NP_650457.2	Gene:	CG34404 / 41873	FlyBaseID:	FBgn0085433	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001028859.1	Gene:	Ushbp1 / 290629	RGDID:	1310859	Length:	680	Species:	Rattus norvegicus

Alignment Length:	733	Identity:	163/733 - (22%)
Similarity:	271/733 - (36%)	Gaps:	178/733 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 GRH-LVGSSDLDSPEHTQRDTTESDNNISSCSTLDIVNKVEQL------SVQQLENRVR---DLT 113
            ||| |.|..|..:....:.|||..          ....|.|.|      |:|...||::   |:.
  Rat    13 GRHPLPGELDPVAESSEEVDTTNG----------SFETKPELLQEHLGPSLQGPGNRIKEDCDVG 67

  Fly   114 QR----LQQAERQLTESNTEREICHKRLEV---------VSQAHECRITEMHCVIAELSKKLRSK 165
            ..    |...||:..|....:.:....|:.         |.:..:||::.:..|:|...:...|.
  Rat    68 SHGVLPLSPEERREPEVEAHQALQEAPLDTGPAEITAPNVYETLKCRLSSLEAVVAAWRRHSLSF 132

  Fly   166 QDHVIMEEQEPDGSELSFQEGSVYNSELNLTNPDAECQTEPLEDFEGACSTTSVGNVAHKPPELS 230
            ...|..|:::|..      .||..|.|                                   |.|
  Rat   133 SKPVEAEDRDPGA------PGSFGNEE-----------------------------------EAS 156

  Fly   231 HKGQVEALQEEVLHLRARIALLQSEISTKDAAVVEEQTKVAFDCESEVNECGQR----LNDLNVC 291
            ..|     |:|..|...|.|.|:..:.|::..:...|..:. |.::| ||..||    |.|
  Rat   157 GPG-----QQEAAHFIERNAWLRLALGTREEELARTQASLQ-DAQAE-NETLQRQVQELED---- 210

  Fly   292 TSLTSPQKRIPAVPKMAERVKLRCASKHESGED----PSQDTSLSNEQINLVEHLVSELKEQNLY 352
             ||...:...|  |.|. |...|.::...||.:    ..||:.:::.   .::.|.|:...|:..
  Rat   211 -SLMQLEASPP--PSML-RAGRRNSNSSSSGAERRPWAPQDSPMAHP---FLQRLRSDSSTQSFG 268

  Fly   353 MENFMEP---LHLSKD-LERLQRRVEQLEMRNTMLALTLDECKEHTEHLYLLCGKYESNAVALQL 413
            ..:...|   ::|.:| :.:||..:|:|:..|.:|...|...|...|.|.:..||.|:.|.||.|
  Rat   269 CLSTQRPSPEMYLMEDQMGQLQGNIEKLKCFNRLLLAVLQGYKGRCESLSIKLGKREAEATALHL 333

  Fly   414 ALNCSDRAIEAYDVMLALLESKLALLGEKSVAAEESRRSVEAVARHLLARLDSEKNVCENSLGPW 478
            ||..|....|.|:|:|||   |.|.||....|.....::.|..|..||.:.:...:|......|.
  Rat   334 ALQYSKDCEEVYEVLLAL---KTAGLGAGVGATNGDLQAAEKEASRLLVKKEVAMDVKTPQPSPE 395

  Fly   479 QHNIN------------------------------LGPEDAPKTGRPWC-ADDDNRLRYH----V 508
            ..:::                              |.|..|||...|.. |.....|...    :
  Rat   396 GSSVDKPTPEELAAQLHGYVQHLRERWALLKIPPVLDPATAPKPTMPHAEATVQTILEIQPGPTL 460

  Fly   509 SKLKGRRSNVQHTIVSLESPFSDIYERKRLALEKEH--ELRSADKKSPIDLETAVIMQEILELRD 571
            .:|:  :|.:|..:.:.....:|:..|.:||..::.  |||.|..::    :...:...:.:||.
  Rat   461 PQLE--KSQIQQDLAATRDGLADLVLRLQLAQREKRGLELREAALRA----QGPALRLLLQQLRW 519

  Fly   572 SNLQL------------KTKMEEAEQERQNANE-RVGILHEALKQLQANNRVSYSEAEHAALTEQ 623
            ....|            .:..|||.::||...: ...:|...:.::..:..||           |
  Rat   520 EQAHLMGDGSSGGSSEDPSSEEEAGEDRQQHYQGPPALLGGQMGKVWDSETVS-----------Q 573

  Fly   624 QLVEALTRETELKGRIQTLLANV-TASQKAFDEKYEQLHQNVRELQKSNHNLGQMLDHTKRKYQL 687
            :|..:|||..:|:.::|:|...: ..:||......:....| |||.|::..|........||.:.
  Rat   574 ELSASLTRAVDLRAQLQSLRRQLEQMAQKGRTRGAQSAELN-RELCKAHSALALAFREAHRKQEE 637

  Fly   688 RVRKLEQKIVDLRLDYEQ 705
            :.|||||::.  |:..:|
  Rat   638 QCRKLEQQMA--RMQAQQ 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34404	NP_650457.2	SCP-1	<99..599	CDD:114219	125/583 (21%)
		MCC-bdg_PDZ	368..432	CDD:287477	25/63 (40%)
		WXG100	609..696	CDD:295131	25/87 (29%)
Ushbp1	NP_001028859.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..101		22/97 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..162		11/72 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	217..250		9/35 (26%)
		MCC-bdg_PDZ	288..352	CDD:287477	26/66 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..562		7/37 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23347
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.990