DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trax and Tsnax

DIOPT Version :9

Sequence 1:	NP_650454.2	Gene:	Trax / 41871	FlyBaseID:	FBgn0038327	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	NP_058605.1	Gene:	Tsnax / 53424	MGIID:	1855672	Length:	290	Species:	Mus musculus

Alignment Length:	284	Identity:	102/284 - (35%)
Similarity:	162/284 - (57%)	Gaps:	24/284 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KNGGAGHR----NTAPRKRQIPAAQLDEDSPIVQQFRIYSNELIMKHDRHERIVKLSRDITIESK 63
            |.|..|.|    :|.|..::.........||::..|:.:..||..:||::||:||||||||:|||
Mouse     4 KEGPGGFRKRKHDTFPHNQRREGKDASLSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESK 68

  Fly    64 RIIFLLHSIDSRKQNKEKVLEEARQRLNKLIAVNFRAVALELRDQDVYQFRSSYSPGLQEFIEAY 128
            |.|||||.|.| ..:.|::|.|:..:|:. :......||.||..:|::||..:.:.||||::||.
Mouse    69 RTIFLLHRITS-APDMEEILTESESKLDG-VRQKILQVAQELSGEDMHQFHRAVTTGLQEYVEAV 131

  Fly   129 TYMEYLCHEDAEGENETKSVSDWQAIQAVMQYVEESS--QPKEEPTEGEDVQAIAQVESPKKFQF 191
            ::..::         :|:|:...:.|...:.:..|.|  :.|..|.||::.|.:.       ::.
Mouse   132 SFQHFI---------KTRSLISMEEINKQLTFTAEDSGKESKTPPAEGQEKQLVT-------WRL 180

  Fly   192 FVDPTEYILGLSDLTGELMRRCINSLGSGDTDTCLDTCKALQHFYSGYISLNCQRARELWRKITT 256
            .:.|.:|:||::||||||||.||||:|:||.||..:..:.|:..|.|:..:......|:.:|:.|
Mouse   181 KLTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYT 245

  Fly   257 MKQSVLKAENVCYNVKVRGGEAAK 280
            :|||:.|.||.||.:||||.|..|
Mouse   246 LKQSLAKVENACYALKVRGSEIPK 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trax	NP_650454.2	Translin-like	37..267	CDD:271348	84/231 (36%)
Tsnax	NP_058605.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31		6/26 (23%)
		Translin-like	42..256	CDD:294622	84/231 (36%)
		Interaction with C1D. /evidence=ECO:0000250	73..208		48/152 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831329
Domainoid	1	1.000	156	1.000	Domainoid score	I4173
eggNOG	1	0.900	-	-		E1_COG2178
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4374
Inparanoid	1	1.050	176	1.000	Inparanoid score	I4033
Isobase	1	0.950	-	1.056642	Normalized mean entropy	S6820
OMA	1	1.010	-	-		QHG55787
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006191
OrthoInspector	1	1.000	-	-		oto92496
orthoMCL	1	0.900	-	-		OOG6_105072
Panther	1	1.100	-	-	LDO	PTHR10741
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1561
SonicParanoid	1	1.000	-	-		X4467
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740