DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5044 and Ehhadh

DIOPT Version :9

Sequence 1:	NP_732020.2	Gene:	CG5044 / 41869	FlyBaseID:	FBgn0038326	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_076226.2	Gene:	Ehhadh / 74147	MGIID:	1277964	Length:	718	Species:	Mus musculus

Alignment Length:	212	Identity:	55/212 - (25%)
Similarity:	98/212 - (46%)	Gaps:	27/212 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 MIILNRPKALNAINLEMVRKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDES 119
            ||.|..| .:|||:..::.::...|:|.....::  ::|.|..|. ||||.|:...  ..||..:
Mouse    13 MIRLCNP-PVNAISPTVITEVRNGLQKASLDHTVRAIVICGANDN-FCAGADIHGF--KSPTGLT 73

  Fly   120 KSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVG 184
            .....:|      |..|:.|.:|.|.|:.:|||:.|::...||:|:.:.....||..:|:.|...
Mouse    74 LGSLVDE------IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGAR 132

  Fly   185 GSYFLPRLQGKLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCPDADDVPELLQK 249
            |:..|||:   :|:.:.|        |:..||......|:.|:..|:..:    .:|.|.|.::.
Mouse   133 GTQLLPRV---VGVPVAL--------DLITSGRHISTDEALKLGILDVVV----KSDPVEEAIKF 182

  Fly   250 YHSPPEKPFSLQPVLEQ 266
            ..:...||...:.:|.:
Mouse   183 AQTVIGKPIEPRRILNK 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5044	NP_732020.2	PRK05617	44..376	CDD:235533	55/212 (26%)
CG5044	NP_732020.2	ECH_2	56..374	CDD:292731	55/212 (26%)
Ehhadh	NP_076226.2	Enoyl-CoA hydratase / isomerase	1..280		55/212 (26%)
		crotonase-like	12..186	CDD:119339	52/197 (26%)
		fadJ	20..702	CDD:236864	51/204 (25%)
		3-hydroxyacyl-CoA dehydrogenase	281..567
		3HCDH_N	297..471	CDD:280833
		3HCDH	473..577	CDD:279114
		3HCDH	614..700	CDD:279114
		Microbody targeting signal. /evidence=ECO:0000250	716..718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900