DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5044 and hadhaa

DIOPT Version :9

Sequence 1:	NP_732020.2	Gene:	CG5044 / 41869	FlyBaseID:	FBgn0038326	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_001098746.1	Gene:	hadhaa / 553401	ZFINID:	ZDB-GENE-031222-5	Length:	761	Species:	Danio rerio

Alignment Length:	295	Identity:	72/295 - (24%)
Similarity:	120/295 - (40%)	Gaps:	60/295 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RTCSQLPMIGGATISQTKPTTMALSVRQSSSSVLATE------SSNKGMIILNRP--------KA 65
            |.|:      |...|.|.....:|||   ||:|||..      ..|..::.:|.|        |.
Zfish    10 RGCT------GVKSSFTGHGQRSLSV---SSAVLARTHVSYEVKDNVAVVRINDPTSKVNTLSKH 65

  Fly    66 LNAINLEMVRKIYKHLKKCEKSKSLVII-KGTGDKAFCAGGDVRALVEAGPTDESKSFFREEYST 129
            :.|..:|::.:::.:    ...||.|:| :..|  .|.||.|:..:......:|..|..:.....
Zfish    66 MQAEMVEVMNEVWGN----SSVKSAVLISRKPG--CFIAGADINMIQACTTAEEVTSLSQAGQKM 124

  Fly   130 NALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVA--SDRTLFAMPETAIGLFPDVGGSYFLPRL 192
            ...|....||.:|.|:|..:|||:..::..:||:|  |.:|:...||..:||.|..||:..||::
Zfish   125 FEQIEKSPIPIVAAINGSCLGGGLEFAIACQYRIATKSKKTVLGTPEVMLGLLPGAGGTQRLPKM 189

  Fly   193 QGKLGLY-LGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCPDADDVPELLQKYHSPPEK 256
            .|....: :.|||..:|.......|: .|.......|.|:                    ||.|:
Zfish   190 VGLPAAFDMMLTGRNIRADKAKKMGL-VHQLVDPLGPGLK--------------------SPEER 233

  Fly   257 PFS-LQPVLEQINKNFSADSV-----EGILENLQN 285
            ... |:.|.....|..:|..|     :|:::.:|:
Zfish   234 TIEYLEEVAVDFAKGLAAKKVTLEKKKGLMQKVQD 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5044	NP_732020.2	PRK05617	44..376	CDD:235533	64/266 (24%)
CG5044	NP_732020.2	ECH_2	56..374	CDD:292731	58/248 (23%)
hadhaa	NP_001098746.1	fa_ox_alpha_mit	25..760	CDD:131494	67/274 (24%)
		crotonase-like	39..249	CDD:119339	55/236 (23%)
		3HCDH_N	361..539	CDD:280833
		3HCDH	542..637	CDD:279114
		3HCDH	674..>750	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900