DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5044 and hibch

DIOPT Version :9

Sequence 1:	NP_732020.2	Gene:	CG5044 / 41869	FlyBaseID:	FBgn0038326	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_001016188.1	Gene:	hibch / 548942	XenbaseID:	XB-GENE-947696	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	349	Identity:	201/349 - (57%)
Similarity:	255/349 - (73%)	Gaps:	11/349 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKS--LVIIKGTGDKAFCAGGDVRAL 110
            |.|::...|:|.|||||||||:||.|:|.||..|...|:...  ||||||.|.||||||||:||:
Frog    38 LLTKAGCAGVITLNRPKALNALNLGMIRLIYPQLGLWEEDPETYLVIIKGVGGKAFCAGGDIRAV 102

  Fly   111 VEAGPTDE--SKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMP 173
            .:||...:  ::.||||||..|..||.||.||:|:||||||||||||||||.:||||:.||||||
Frog   103 TDAGKAGDRLAQDFFREEYILNNAIGTYKKPYVALIDGITMGGGVGLSVHGHFRVASENTLFAMP 167

  Fly   174 ETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETAL--LN 236
            ||||||||||||.||||||.|||||||.|||:||:|:||..:|||||:.||.|||.||..|  :.
Frog   168 ETAIGLFPDVGGGYFLPRLPGKLGLYLALTGFRLKGSDVQKAGIATHFVESEKIPSLEQDLVAMK 232

  Fly   237 CPDADDVPELLQKYH----SPPEKPFSLQPVLEQINKNFSADSVEGILENLQNDGSEWAKKTLET 297
            ||..::|.::|..||    :..:|||.|...|::||..|||.|||.|:|||:.|||.:|.|.|:|
Frog   233 CPSKENVADVLDSYHNKSYAAQDKPFVLAEHLDKINSLFSASSVEAIIENLRCDGSSFALKQLQT 297

  Fly   298 LSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTK 362
            ||.|||||:|:|||||:.||.:||.:.|.|||||:...::..||.|||||:||||:|..:|.|..
Frog   298 LSTMSPTSLKITFRQLKEGSSMSLQEVLTMEYRLSQACMKGYDFYEGVRAVLIDKNQNAKWNPEL 362

  Fly   363 LADVTEEHVQWFFRKLPDTEELKL 386
            |.:||::::..:|..|.:: :|||
Frog   363 LEEVTDDYIDSYFTSLGNS-DLKL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5044	NP_732020.2	PRK05617	44..376	CDD:235533	196/337 (58%)
CG5044	NP_732020.2	ECH_2	56..374	CDD:292731	194/327 (59%)
hibch	NP_001016188.1	ECH_2	45..375	CDD:379770	194/329 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	374	1.000	Domainoid score	I869
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5607
Inparanoid	1	1.050	378	1.000	Inparanoid score	I2028
OMA	1	1.010	-	-		QHG63150
OrthoDB	1	1.010	-	-		D1369862at2759
OrthoFinder	1	1.000	-	-		FOG0001715
OrthoInspector	1	1.000	-	-		otm49530
Panther	1	1.100	-	-	LDO	PTHR43176
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4091
SonicParanoid	1	1.000	-	-		X1442
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110