Protein Alignment Hibch and Echdc2

DIOPT Version :10

• Sequence 1: NP_732020.2
• Gene: Hibch / 41869
• FlyBaseID: FBgn0038326
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_001100145.1
• Gene: Echdc2 / 298381
• RGDID: 1308525
• Length: 296
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 73/333 - (21%)
• Similarity: 132/333 - (39%)
• Gaps: 85/333 - (25%)

  Fly    39 SVRQSSSSVLATESSNKGM--IILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVI------IKG 95
            |.|.....|.|....|:|:  |::|||.|.||:....|.::.:.|.:..:.:.:.:      :||
  Rat    28 STRTPEIQVQALTGPNQGITEILMNRPHARNALGNVFVSELLEALAQLREDQQVRVLLFRSAVKG 92

  Fly    96 TGDKAFCAGGDVR-----ALVEAGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGL 155
                .||||.|::     :..|.|      :|.:......:.|..:..|.||.:||..:|||:.|
  Rat    93 ----VFCAGADLKERERMSAAEVG------TFVQRLRGLMSEIAAFPAPTIAAMDGFALGGGLEL 147

  Fly   156 SVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQG-KLGLYLGLTGYRLRGADVYYSGIAT 219
            ::....|:|:...:..:.||..||.|..||:..|||..| .|...|..||.||.|...:..|:..
  Rat   148 ALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLNGVQAHELGLVN 212

  Fly   220 HYCESSKIPDLETALLNCPDADDVPELLQKYHSPPEKPFSL-QPVLEQINKNFSADSVEGILENL 283
            |....::..|                  ..||    :..:| |.:|.|
  Rat   213 HAVAQNEEGD------------------AAYH----RALALAQEILPQ----------------- 238

  Fly   284 QNDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRAL 348
                              :|.::::....::.|.::.:|..:.:|:....:::...|..||:.|.
  Rat   239 ------------------APIAVRLGKVAIDRGMEVDIASGMAIEHMCYAQNIPTQDRLEGMAAF 285

  Fly   349 LIDKDQKP 356
               ::::|
  Rat   286 ---REKRP 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hibch	NP_732020.2	ECH_2	56..375	CDD:465024	68/316 (22%)
Echdc2	NP_001100145.1	crotonase-like	42..296	CDD:474030	69/319 (22%)