DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5044 and Ehhadh

DIOPT Version :9

Sequence 1:	NP_732020.2	Gene:	CG5044 / 41869	FlyBaseID:	FBgn0038326	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_598290.1	Gene:	Ehhadh / 171142	RGDID:	621441	Length:	722	Species:	Rattus norvegicus

Alignment Length:	207	Identity:	54/207 - (26%)
Similarity:	97/207 - (46%)	Gaps:	31/207 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 MIILNRPKALNAINLEMVRKIYKHLKKCEKS---KSLVIIKGTGDKAFCAGGDVRALVEAGPTDE 118
            ||.|..| .:||::..::|::...|:|....   |::||....|:  ||||.|:...
  Rat    13 MIRLCNP-PVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGN--FCAGADIHGF-------- 66

  Fly   119 SKSFFREEYSTNAL---IGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLF 180
              |.|....:..:|   |..|:.|.:|.|.|:.:|||:.|::...||:|:.:....:||..:|:.
  Rat    67 --SAFTPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEVTLGIL 129

  Fly   181 PDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCPDADDVPE 245
            |...|:..|||:   :|:.:.|        |:..||......|:.::..|:..:.:.| .::..:
  Rat   130 PGARGTQLLPRV---VGVPVAL--------DLITSGKYLSADEALRLGILDAVVKSDP-VEEAIK 182

  Fly   246 LLQKYHSPPEKP 257
            ..||....|.:|
  Rat   183 FAQKIIDKPIEP 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5044	NP_732020.2	PRK05617	44..376	CDD:235533	54/207 (26%)
CG5044	NP_732020.2	ECH_2	56..374	CDD:292731	54/207 (26%)
Ehhadh	NP_598290.1	Enoyl-CoA hydratase / isomerase	1..281		54/207 (26%)
		crotonase-like	12..187	CDD:119339	51/198 (26%)
		fadJ	20..706	CDD:236864	50/199 (25%)
		3-hydroxyacyl-CoA dehydrogenase	282..571
		3HCDH_N	298..475	CDD:280833
		3HCDH	477..581	CDD:279114
		3HCDH	618..704	CDD:279114
		Microbody targeting signal	720..722
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900