Protein Alignment CG5044 and ECI1

DIOPT Version :9

• Sequence 1: NP_732020.2
• Gene: CG5044 / 41869
• FlyBaseID: FBgn0038326
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_001910.2
• Gene: ECI1 / 1632
• HGNCID: 2703
• Length: 302
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 63/305 - (20%)
• Similarity: 124/305 - (40%)
• Gaps: 53/305 - (17%)

  Fly    15 RTCSQLPMIGGATISQTKPTTMA--LSVRQSSSSVLATESSNKGMIIL---NRPKALNAINLEMV 74
            |..::||   ||.:.:|:.....  .:.|..|..||....:..|:.::   |.|  :|:::||.:
Human    16 RAGARLP---GAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVMKFKNPP--VNSLSLEFL 75

  Fly    75 RKIYKHLKKCEKSKSL--VIIKGTGDKAFCAGGDVRALVEAGPTDES------KSFFREEYSTNA 131
            .::...|:|.|..||.  ||:.......|.||.|:..:....|...:      :..:...|.:|.
Human    76 TELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNL 140

  Fly   132 LIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASD--RTLFAMPETAIGLFPDVGGSYFLPRLQG 194
            ::       ::.|:|....||..:::...||:.:|  |....:.||.:|:   :...:....|:.
Human   141 VL-------VSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQLGI---IAPFWLKDTLEN 195

  Fly   195 KLG-------LYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETAL------LNCPD-ADDVPE 245
            .:|       |.|||.   ...|:....||........::.  .|||      :..|| |..:.:
Human   196 TIGHRAAERALQLGLL---FPPAEALQVGIVDQVVPEEQVQ--STALSAIAQWMAIPDHARQLTK 255

  Fly   246 LLQKYHSP----PEKPFSLQPVLEQINKNFSADSVEGILENLQND 286
            .:.:..:.    .::...:|..:..|:|:....|::..||.|:.:
Human   256 AMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5044	NP_732020.2	PRK05617	44..376	CDD:235533	56/274 (20%)
		ECH_2	56..374	CDD:292731	53/262 (20%)
ECI1	NP_001910.2	ECH_1	52..298	CDD:306810	52/262 (20%)
		Substrate binding. /evidence=ECO:0000269|PubMed:15351645, ECO:0007744|PDB:1SG4	106..110		2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810