Protein Alignment Atg4b and Atg4a

DIOPT Version :9

• Sequence 1: NP_650452.1
• Gene: Atg4b / 41868
• FlyBaseID: FBgn0038325
• Length: 668
• Species: Drosophila melanogaster
• Sequence 2: NP_001366610.1
• Gene: Atg4a / 666468
• MGIID: 2147903
• Length: 463
• Species: Mus musculus
• Alignment Length: 374
• Identity: 127/374 - (33%)
• Similarity: 194/374 - (51%)
• Gaps: 56/374 - (14%)

  Fly   233 PQQIDEIVV--PQELGMD----------AVENQV--------------------GEQ-PWEEGIE 264
            |:.:::.||  |.||..|          ..|||:                    |:| |.:....
Mouse    46 PESLEKAVVKLPVELAQDDSWRMESVMSKYENQILIFPDYLEEFPDTDELVWILGKQHPLKTEKS 110

  Fly   265 GFRRDFYSRIWMTYRREFPIMNGSNYTSDCGWGCMLRSGQMLFAQGLICHFLGRSWRYDSESQLH 329
            ....|..:|:|.||||:|..:.|:..:||.|||||||.|||:.||.|||..|||.|.::.:.:..
Mouse   111 KLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWERQKEQP 175

  Fly   330 STYEDNMHKKIVKWFGDSSSKSSPFSIHALVRLGEHLGKKPGDWYGPASVSYLLKHALEHAAQEN 394
            ..|:     :|::.|.|  .|...:|||.:.::|...||..|:|:||.:|:.::|        :.
Mouse   176 KEYQ-----RILQCFLD--RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVIK--------KL 225

  Fly   395 ADFD---NISVYVAKDCTIYLQDIEDQCSI-PEPAPKPHVPWQQAKRPQAETTKTEQQQHWKSLI 455
            |.||   :::|||:.|.|:.::||:..|.: |..|..|...:..|.....:|  :.....||.|:
Mouse   226 ALFDEWNSLAVYVSMDNTVVIEDIKKMCCVLPVGAADPAGDFLTASNQSRDT--SVPCSAWKPLL 288

  Fly   456 VLIPLRLGSDKLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLDPHYCQEMVDV 520
            :::|||||.:::||||....|........||.|||||.::.||:||..|.||.||||..|..||:
Mouse   289 LIVPLRLGINQINPVYVEAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDI 353

  Fly   521 NQENF-SLHSFHC-KSPRKLKASKMDPSCCIGFYCATKSDFDNFMESVQ 567
            .:... ...:||| :||:::....:|||..:||:|..:.||||:...||
Mouse   354 EESGLVDDQTFHCLQSPQRMSILNLDPSVALGFFCKEEKDFDNWCSLVQ 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	264..565	CDD:281417	112/306 (37%)
Atg4a	NP_001366610.1	Peptidase_C54	109..399	CDD:397471	112/306 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R109
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750