Protein Alignment Atg4b and atg4b

DIOPT Version :9

• Sequence 1: NP_650452.1
• Gene: Atg4b / 41868
• FlyBaseID: FBgn0038325
• Length: 668
• Species: Drosophila melanogaster
• Sequence 2: XP_005165980.1
• Gene: atg4b / 448859
• ZFINID: ZDB-GENE-040917-3
• Length: 424
• Species: Danio rerio
• Alignment Length: 542
• Identity: 148/542 - (27%)
• Similarity: 220/542 - (40%)
• Gaps: 184/542 - (33%)

  Fly   154 WHNVKYGWSGKMRQTSFSKEQPVWLLGRCYHRRFTPPVSMESSITELPSGADTTPDNATSAFDSI 218
            :.::::|......:||    .|||:||:.:           |::||.
Zfish    38 YDSLRFGEIEDFPETS----DPVWILGKQF-----------SALTEK------------------ 69

  Fly   219 QATSTSTSLYPALNPQQIDEIVVPQELGMDAVENQVGEQPWEEGIEGFRRDFYSRIWMTYRREFP 283
                              |:|:.                           |..||:|.|||:.|.
Zfish    70 ------------------DDILA---------------------------DVTSRLWFTYRKNFQ 89

  Fly   284 IMNGSNYTSDCGWGCMLRSGQMLFAQGLICHFLGRSWRYDSESQLHSTYEDNMHKKIVKWFGDSS 348
            .:.|:..|||.|||||||.|||:..:.|||..|||.|::....:....|...::..|.|
Zfish    90 PIGGTGPTSDTGWGCMLRCGQMILGEALICRHLGRDWKWSPGQRQRPEYVSILNAFIDK------ 148

  Fly   349 SKSSPFSIHALVRLGEHLGKKPGDWYGPASVSYLLKHALEHAAQENADFDN---ISVYVAKDCTI 410
             |.|.:|||.:.::|...||..|.||||.:|:.:||        :.|.||:   ::|:||.|.|:
Zfish   149 -KDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLK--------KLAVFDSWSRLAVHVAMDNTV 204

  Fly   411 YLQDIEDQCSIPEPAPKPHVPWQQAKRPQAETTKTEQQQH----------------WKSLIVLIP 459
            .:::|:..|          :||....|.....::..::.:                ||.|::|||
Zfish   205 VIEEIKRLC----------MPWLDFDRGACAVSEEPREMNGDLEGACALAEEETALWKPLVLLIP 259

  Fly   460 LRLGSDKLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLDPHYCQEMVDVNQE- 523
            ||||...:|..|...||........||::||||..:.||:||..|.||:||||..|..||.:::
Zfish   260 LRLGLSDINEAYIEPLKQCFMMPQSLGVIGGKPNSAHYFIGFVGDELIYLDPHTTQPAVDPSEDG 324

  Fly   524 NFSLHSFHCKSPR-KLKASKMDPSCCIGFYCATKSDFDNFMESVQLYLHPMRCASGATVDKAAGS 587
            :|...|:||:.|. ::...::|||...||:|.|:.|||::            ||....|....|
Zfish   325 HFPDDSYHCQHPPCRMHICELDPSIAAGFFCQTEDDFDDW------------CAQIRKVSNCRG- 376

  Fly   588 HHTTPQSSHQTEQTEMNYPLFSFSRGRCMDHERDEMSDSLYKPLIKQVASLAQELGAQLAPPQHG 652
                             .|:|             |:.||....||     .|..|  .|.|
Zfish   377 -----------------LPMF-------------ELVDSQPSHLI-----TADVL--NLTP---- 400

  Fly   653 DEHDQD------DSESEEFVLL 668
            |..|.|      |||.|||.:|
Zfish   401 DFSDSDRLERFFDSEDEEFEIL 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	264..565	CDD:281417	110/321 (34%)
atg4b	XP_005165980.1	Peptidase_C54	70..367	CDD:281417	113/360 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R109
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750