Protein Alignment Atg4b and Atg4a

DIOPT Version :9

• Sequence 1: NP_650452.1
• Gene: Atg4b / 41868
• FlyBaseID: FBgn0038325
• Length: 668
• Species: Drosophila melanogaster
• Sequence 2: NP_608563.1
• Gene: Atg4a / 33283
• FlyBaseID: FBgn0031298
• Length: 411
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 114/367 - (31%)
• Similarity: 176/367 - (47%)
• Gaps: 55/367 - (14%)

  Fly   217 SIQATSTSTSLYPA-LNPQQIDEIVVPQELGMDAVEN--QVGEQPWEEG--------IEGFRRDF 270
            |.|......|::.| |.|..:....|.|.:|....|:  :.....|..|        :|..|||.
  Fly     6 SDQLARIMESVFEAYLGPDSVLASAVGQAVGSGEPEDIPRRNTDVWVLGKKYNAIQELELIRRDI 70

  Fly   271 YSRIWMTYRREFPIMNGSNYTSDCGWGCMLRSGQMLFAQGLICHFLGRSWRYDSESQLHSTYEDN 335
            .||:|.|||..|..:.....|:|.|||||||.|||:.||.||...|||.|.:..:.:      |.
  Fly    71 QSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTPDCR------DA 129

  Fly   336 MHKKIVKWFGDSSSKSSPFSIHALVRLGEHLGKKPGDWYGPASVSYLLKHALEHAAQENADFDNI 400
            .:.|||..|.|  .::|.:|||.:.::||...|..|:|.||.:|:.:||..:..     .|:.::
  Fly   130 TYLKIVNRFED--VRNSFYSIHQIAQMGESQNKAVGEWLGPNTVAQILKKLVRF-----DDWSSL 187

  Fly   401 SVYVAKDCTIYLQDIEDQCSIPEPAPKPHVPWQQAKRPQAETTKTEQQQHWKSLIVLIPLRLGSD 465
            :::||.|.|:.|.|:...|                          .:...||.|:::||||||..
  Fly   188 AIHVAMDSTVVLDDVYASC--------------------------REGGSWKPLLLIIPLRLGIT 226

  Fly   466 KLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLDPHYCQEMVDVNQENFSL--- 527
            .:||:|...||..|..:...|::||:|..:|||:|:.:|.:::||||..|....|.|:..:.
  Fly   227 DINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTAAAEQD 291

  Fly   528 --HSFHCKSPRKLKASKMDPSCCIGFYCATKSDFDNFMESVQ 567
              .::|.|...:|..|.||||..:.|.|.|...|::.:..::
  Fly   292 YDETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLK 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	264..565	CDD:281417	102/305 (33%)
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	101/300 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449512
Domainoid	1	1.000	109	1.000	Domainoid score	I1620
eggNOG	1	0.900	-	-		E1_KOG2674
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D114782at6656
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	1	1.000	-	-		otm46790
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	1	1.100	-	-	P	PTHR22624
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R109
SonicParanoid	1	1.000	-	-		X289
	11	10.780