Protein Alignment Atg4b and atg4

DIOPT Version :9

• Sequence 1: NP_650452.1
• Gene: Atg4b / 41868
• FlyBaseID: FBgn0038325
• Length: 668
• Species: Drosophila melanogaster
• Sequence 2: NP_594771.1
• Gene: atg4 / 2542182
• PomBaseID: SPAC19B12.08
• Length: 320
• Species: Schizosaccharomyces pombe
• Alignment Length: 319
• Identity: 92/319 - (28%)
• Similarity: 135/319 - (42%)
• Gaps: 65/319 - (20%)

  Fly   253 QVGEQPWEEGIEGFRRDFYSRIWMTYRREFPIMNGSNYTSDCGWGCMLRSGQMLFAQGL-ICHFL 316
            ::.:..|.   |.|..|.:|.|.:|||.  .|....|.|||.|||||:||.|.|.|..| ||:
pombe    34 KIEDSQWP---EKFLYDSFSLITITYRS--GIEGLENMTSDTGWGCMIRSTQTLLANCLRICY-- 91

  Fly   317 GRSWRYDSESQLHSTYEDNMHKKIVKWFGDSSSKSSPFSIHALVRLGEHL-GKKPGDWYGPASVS 380
                   .|.||         |:|:..|.|  ..|:|||||..|.:|:.| ...||.|:||.:..
pombe    92 -------PEKQL---------KEILALFAD--EPSAPFSIHQFVTMGKTLCDINPGQWFGPTTSC 138

  Fly   381 YLLKHALEHAAQENADFDNISVYVAKDCTIYLQDIEDQCSIPEPAPKPHVPWQQAKRPQAETTKT 445
                ..:...:.:|.|.. :.||||::.....:|...:.|.|
pombe   139 ----SCVARLSDQNPDVP-LHVYVARNGNAIYRDQLSKVSFP----------------------- 175

  Fly   446 EQQQHWKSLIVLIPLRLGSDKLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLD 510
                    :::|||.|||.|.:|..|...|..:......:||.||:|:.:.||...|.....:||
pombe   176 --------VLLLIPTRLGIDSINESYYDQLLQVFEIRSFVGITGGRPRSAHYFYARQNQYFFYLD 232

  Fly   511 PHYCQEMVDVNQENFSLHSFHCKSPRKLKASKMDPSCCIGFYCATKSDFDNFMESVQLY 569
            || |........:..|..:||..:.|::....:||....||....:.::.:| |:.|.|
pombe   233 PH-CTHFAHTTTQPASEETFHSATLRRVAIQDLDPCMIFGFLIRDEEEWHSF-EANQKY 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	264..565	CDD:281417	88/302 (29%)
atg4	NP_594771.1	Peptidase_C54	42..283	CDD:281417	87/299 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	109	1.000	Domainoid score	I1620
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	1	1.000	-	-		otm47244
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	1	1.100	-	-	LDO	PTHR22624
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R109
SonicParanoid	1	1.000	-	-		X289
TreeFam	1	0.960	-	-
	11	10.800