Protein Alignment Atg4b and atg-4.1

DIOPT Version :9

• Sequence 1: NP_650452.1
• Gene: Atg4b / 41868
• FlyBaseID: FBgn0038325
• Length: 668
• Species: Drosophila melanogaster
• Sequence 2: NP_001368160.1
• Gene: atg-4.1 / 190777
• WormBaseID: WBGene00013595
• Length: 481
• Species: Caenorhabditis elegans
• Alignment Length: 457
• Identity: 116/457 - (25%)
• Similarity: 198/457 - (43%)
• Gaps: 105/457 - (22%)

  Fly   260 EEGIEGFRRDFYSRIWMTYRREFPIMNGSNYTSDCGWGCMLRSGQMLFAQGLICHFLGRSWRYDS 324
            |:|||..::...||.|.||||:|..:.|:..::|.|||||||..|||..:.|:...:||.:.:|.
 Worm    74 EDGIEAMKKYVTSRFWFTYRRDFSPIGGTGPSTDQGWGCMLRCAQMLLGEVLLRRHIGRHFEWDI 138

  Fly   325 ESQLHSTYEDNMHKKIVKWFGDSSSKSSPFSIHALVRLGEHLGKKPGDWYGPASVSYLLKHALEH 389
            |.      ...:::||::.|.|  .|.:.:|||.:.::|...||:...|:||.:.:.::|.....
 Worm   139 EK------TSEIYEKILQMFFD--EKDALYSIHQIAQMGVTEGKEVSKWFGPNTAAQVMKKLTIF 195

  Fly   390 AAQENADFDNISVYVAKDCTIYLQD-IEDQCSIP-EPAPKPHVPWQQAKRPQAETTKTEQQQHWK 452
                 .|:.||:|:||.|..:..:| |....|.| |.|.|..:......:.:...:.......|:
 Worm   196 -----DDWSNIAVHVALDNILVKEDAITMATSYPSEDAVKLIMENGLVDKNRLSLSPGNIIPEWR 255

  Fly   453 SLIVLIPLRLGSDKLNPVYAHCLKLLLSTEHCLGILGGKPKHSLYFVGFQEDRLIHLDPHYC--- 514
            .|:::||||||...:||.|...::.......|:||:||:|.|:|||||....:|.:||||||
 Worm   256 PLLLMIPLRLGLTTINPCYLSAIQEFFKIPQCVGIIGGRPNHALYFVGMSGSKLFYLDPHYCRPK 320

  Fly   515 -------------------------QEMVDVNQENFSLH------SFHCKSPRKLKASKMDPSCC 548
                                     :|:|.:..:...::      ::||:....::...:|||..
 Worm   321 TESTAKMYAEKDSTATTDDVGFSHLEELVPLPSQTADVYTKMDDSTYHCQMMLWIEYENVDPSLA 385

  Fly   549 IGFYCATKSDFDNFMESVQLYLHPMRCASGATVDKAAGSHHTTPQSSHQTEQTEMNYPLFSFSRG 613
            :..:|.|:.:|:|..|::|                     .||..:|..        |:|.|.:.
 Worm   386 LAMFCETRDEFENLCETLQ---------------------KTTLPASQP--------PMFEFLQR 421

  Fly   614 RCMDHERDEMSDSLYKPLIKQVASLA--------QELGAQLAP--------PQHGDEHDQDDSES 662
            |           ..|.|..:....::        .::||....        ..|.:|.|.|:...
 Worm   422 R-----------PKYLPKFEPYTGVSMKIEMKEFDDIGAANVKIDDDFEVLDVHTEEEDADEDND 475

  Fly   663 EE 664
            ::
 Worm   476 DD 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	264..565	CDD:281417	96/336 (29%)
atg-4.1	NP_001368160.1	Peptidase_C54	77..401	CDD:397471	97/336 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820