Protein Alignment Atg4b and atg4db

DIOPT Version :9

• Sequence 1: NP_650452.1
• Gene: Atg4b / 41868
• FlyBaseID: FBgn0038325
• Length: 668
• Species: Drosophila melanogaster
• Sequence 2: XP_009297433.2
• Gene: atg4db / 100329304
• ZFINID: ZDB-GENE-131025-1
• Length: 460
• Species: Danio rerio
• Alignment Length: 582
• Identity: 202/582 - (34%)
• Similarity: 269/582 - (46%)
• Gaps: 198/582 - (34%)

  Fly   133 PG------DLSANRTPTKGMESKLVAMWHNVKY-GWSGKMRQTSFSKEQPVWLLGRCYHRRFTPP 190
            ||      |:..::..|| ::|||::.||||:| |||.|.: ...||..||.|||:.|
Zfish    31 PGLLDFSADVQGSKEKTK-LKSKLMSAWHNVRYRGWSLKSK-PRLSKSSPVCLLGQSY------- 86

  Fly   191 VSMESSITELPSGADTTPDNATSAFDSIQATSTSTSLYPALNPQQIDEIVVPQELGMDAVENQVG 255
                                        |.:||...
Zfish    87 ----------------------------QLSSTGVR----------------------------- 94

  Fly   256 EQPWEEGIEGFRRDFYSRIWMTYRREFPIMNGSNYTSDCGWGCMLRSGQMLFAQGLICHFLGRSW 320
                    |.|||.|.|.:||:|||.|..::||..:||.||||||||.|||.||||:.|.:...|
Zfish    95 --------ESFRRVFSSLLWMSYRRGFRPLDGSTLSSDAGWGCMLRSAQMLLAQGLLLHIMPNGW 151

  Fly   321 RY--------------DSESQL-HS---------------TYEDNMHKKIVKWFGDSSSKSSPFS 355
            .:              |:...| ||               ::|:..|::||.||||  ..|:||.
Zfish   152 TWPATHNQTKDDLEVLDAHGSLRHSGKSRRCSLGSALDGESHEERSHRRIVSWFGD--LPSAPFG 214

  Fly   356 IHALVRLGEHLGKKPGDWYGPASVSYLLKHALEHAAQENADFDNISVYVAKDCTIYLQDIEDQCS 420
            :|.||.||...||:.|||||||..:::|:.|:  :|.|.:|   :.||||:|||:|..|:.:.|
Zfish   215 LHRLVELGRAFGKRAGDWYGPAIAAHILQKAV--SASELSD---LVVYVAQDCTVYTGDVLNLC- 273

  Fly   421 IPEPAPKPHVPWQQAKRPQAETTKTEQQQHWKSLIVLIPLRLGSDKLNPVYAHCLKLLLSTEHCL 485
                         :..|..|....|   ..||||::|:|:|||||.|||||..|:|.||....||
Zfish   274 -------------RTSRTDASWRST---SGWKSLVLLVPVRLGSDGLNPVYTGCVKRLLELRCCL 322

  Fly   486 GILGGKPKHSLYFVGFQEDRLIHLDPHYCQEMVDVNQENFSLHSFHCKSPRKLKASKMDPSCCIG 550
            ||:||||||||||:|||.|:||:|||||||..|||.|::|.|.|||||:.||:..|:|||||.:|
Zfish   323 GIIGGKPKHSLYFLGFQNDQLIYLDPHYCQSAVDVQQDHFPLESFHCKTVRKMAFSRMDPSCTVG 387

  Fly   551 FYCATKSDFDNFMESVQLYLHPMRCASGATVDKAAGSHHTTPQSSHQTEQTEMNYPLFSFSRGRC 615
            ||..:::||.:.            |:.   |.||..|             :|..||:|:|..|..
Zfish   388 FYARSRADFHSL------------CSD---VSKALSS-------------SEQKYPIFTFVEGHS 424

  Fly   616 ---------MDHERDEMSDSLYKPLIKQVASLAQELGAQLAPPQHGDEHDQDDSESEEFVLL 668
                     ||....:..|.|                          ..:|..|.:||||||
Zfish   425 EGQSGSTSDMDITHTKTKDKL--------------------------RRNQKRSSTEEFVLL 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	264..565	CDD:281417	151/330 (46%)
atg4db	XP_009297433.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581284
Domainoid	1	1.000	282	1.000	Domainoid score	I1615
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	328	1.000	Inparanoid score	I2444
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	1	1.000	-	-		otm25992
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	1	1.100	-	-	O	PTHR22624
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.900