DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg4b and cyp2b6

DIOPT Version :9

Sequence 1:	NP_650452.1	Gene:	Atg4b / 41868	FlyBaseID:	FBgn0038325	Length:	668	Species:	Drosophila melanogaster
Sequence 2:	NP_001096373.1	Gene:	cyp2b6 / 100124967	XenbaseID:	XB-GENE-5779150	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	241	Identity:	49/241 - (20%)
Similarity:	76/241 - (31%)	Gaps:	73/241 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ICGQDADPLSLPLVEDGAIEEEQAAPIQTIHRTVFAV-PRVPSPSPVSTSGANL------NLKTE 89
            :||.||       |:|..|.          |...|:. |::|....|| .|..|      |.|..
Frog    78 LCGTDA-------VKDALIN----------HADEFSERPKIPIFEDVS-KGYGLIFSHGENWKVM 124

  Fly    90 NAATATPQRKISTSSRFMNAFSQLYGGGNSGPSCGHVEQHNEEPGDLSANRTPT---KGMESKL- 150
            ...|.|..|.              :|.|..     .:|:...|..|.......:   |..|:.|
Frog   125 RRFTLTTLRD--------------FGMGKK-----TIEERICEESDCLVEAFKSYKGKPFENTLI 170

  Fly   151 -----------VAMWHNVKYGWSGKMRQTSFSKEQPVWLLGRCYHRRFTPPVSM----ESSITEL 200
                       :.:.|...|..:..::......|. |.|:|       :|.|.:    .|.:..|
Frog   171 MNAAVANIIVSILLGHRFDYQDTALLKLIKIINEN-VRLMG-------SPMVMLYNTYPSVMQWL 227

  Fly   201 PSGADTTPDNATSAFDSIQATSTSTSLYPALNPQQ--IDEIVVPQE 244
            |....|..:|....|..::.|.|.......:|.|:  :|..:|.|:
Frog   228 PGKHKTVAENTLKLFKFLEETFTKHRDQLDVNDQRDLVDTFLVKQQ 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg4b	NP_650452.1	Peptidase_C54	264..565	CDD:281417
cyp2b6	NP_001096373.1	p450	31..466	CDD:306555	49/241 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165166911
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930