DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5038 and CYC8

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_009670.3 Gene:CYC8 / 852410 SGDID:S000000316 Length:966 Species:Saccharomyces cerevisiae


Alignment Length:403 Identity:78/403 - (19%)
Similarity:140/403 - (34%) Gaps:120/403 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   420 RQRATDWLNEEQLFKSALQVCP------DNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYE 478
            :|:......::|..::|:...|      ..|:...:||.||..:|:..:|...|...::..|:..
Yeast    16 QQQQQQQQQQQQQQQAAVPQQPLDPLTQSTAETWLSIASLAETLGDGDRAAMAYDATLQFNPSSA 80

  Fly   479 SALMNLGNLYREHGQLSTAEEYIRLAL------------------------QAYPAF-------- 511
            .||.:|.:|||.......|.|....||                        :||.|:        
Yeast    81 KALTSLAHLYRSRDMFQRAAELYERALLVNPELSDVWATLGHCYLMLDDLQRAYNAYQQALYHLS 145

  Fly   512 ----PAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVC---YYNMGNLYLEQKRYAEALH-- 567
                |..|..:||:....|..|.|..::.|.|:...:|...   |:.:|.:|..|.::::||.  
Yeast   146 NPNVPKLWHGIGILYDRYGSLDYAEEAFAKVLELDPHFEKANEIYFRLGIIYKHQGKWSQALECF 210

  Fly   568 ----------------------------HWQ-------HAVALNPRQPKAWANILTMLDNKGLQ- 596
                                        .||       |.:|.|....|....:..:.....:| 
Yeast   211 RYILPQPPAPLQEWDIWFQLGSVLESMGEWQGAKEAYEHVLAQNQHHAKVLQQLGCLYGMSNVQF 275

  Fly   597 ---DDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLY 658
               ..||....::|:..|:|.:..:....|......||.|...:::.:..:..|.::..::||||
Yeast   276 YDPQKALDYLLKSLEADPSDATTWYHLGRVHMIRTDYTAAYDAFQQAVNRDSRNPIFWCSIGVLY 340

  Fly   659 HRWDKTQEAIEAYRTAISIS------------------------------AARATT----ARENL 689
            ::..:.::|::||..||.::                              |||...    .||.|
Yeast   341 YQISQYRDALDAYTRAIRLNPYISEVWYDLGTLYETCNNQLSDALDAYKQAARLDVNNVHIRERL 405

  Fly   690 SKLLKRLEREAQV 702
            ..|.|:||....:
Yeast   406 EALTKQLENPGNI 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 74/372 (20%)
TPR_1 444..477 CDD:278916 9/32 (28%)
TPR repeat 444..472 CDD:276809 8/27 (30%)
TPR_17 466..499 CDD:290167 9/32 (28%)
TPR repeat 480..506 CDD:276809 10/49 (20%)
TPR repeat 511..541 CDD:276809 9/41 (22%)
TPR_1 512..545 CDD:278916 9/32 (28%)
TPR_1 546..577 CDD:278916 10/70 (14%)
TPR repeat 546..574 CDD:276809 9/67 (13%)
TPR repeat 580..608 CDD:276809 4/31 (13%)
TPR repeat 614..642 CDD:276809 4/27 (15%)
TPR repeat 647..677 CDD:276809 10/29 (34%)
CYC8NP_009670.3 TPR <38..142 CDD:223533 22/103 (21%)
TPR repeat 46..74 CDD:276809 8/27 (30%)
TPR repeat 80..108 CDD:276809 9/27 (33%)
TPR 94..391 CDD:223533 49/296 (17%)
TPR repeat 113..143 CDD:276809 3/29 (10%)
TPR repeat 150..178 CDD:276809 8/27 (30%)
TPR repeat 184..211 CDD:276809 6/26 (23%)
TPR repeat 223..253 CDD:276809 3/29 (10%)
TPR repeat 258..290 CDD:276809 4/31 (13%)
TPR repeat 296..324 CDD:276809 4/27 (15%)
TPR repeat 329..359 CDD:276809 10/29 (34%)
TPR repeat 364..393 CDD:276809 1/28 (4%)
Herpes_BLLF1 <697..944 CDD:282904
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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