DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5038 and TTC13

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_078801.3 Gene:TTC13 / 79573 HGNCID:26204 Length:860 Species:Homo sapiens


Alignment Length:247 Identity:60/247 - (24%)
Similarity:96/247 - (38%) Gaps:69/247 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   441 PDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQL-------STAE 498
            ||..:|....|.:.:.:|...:|.....:||:|.|:        ..|||..|.|       :||.
Human   213 PDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS--------ARLYRHRGTLYFISEDYATAH 269

  Fly   499 EYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYA 563
            |..:.:|:.....|.|.:..|:....:|...:|:.|:::|||.:.:|...|.::|..|.|...:.
Human   270 EDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFE 334

  Fly   564 EALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVL---G 625
            .|...:|.|:.||                                  .|.|..|.:|..:|   |
Human   335 AATESFQKALLLN----------------------------------QNHVQTLQLRGMMLYHHG 365

  Fly   626 KLKHYTEAEAIYKRVIELEPHNT-------LYHTNLGVLYHRWDKTQEAIEA 670
            .|:   ||...:||.::|||:|.       |.|..:|..|       |.|:|
Human   366 SLQ---EALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFY-------EGIKA 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 59/246 (24%)
TPR_1 444..477 CDD:278916 8/32 (25%)
TPR repeat 444..472 CDD:276809 5/27 (19%)
TPR_17 466..499 CDD:290167 11/39 (28%)
TPR repeat 480..506 CDD:276809 8/32 (25%)
TPR repeat 511..541 CDD:276809 8/29 (28%)
TPR_1 512..545 CDD:278916 9/32 (28%)
TPR_1 546..577 CDD:278916 8/30 (27%)
TPR repeat 546..574 CDD:276809 7/27 (26%)
TPR repeat 580..608 CDD:276809 0/27 (0%)
TPR repeat 614..642 CDD:276809 10/30 (33%)
TPR repeat 647..677 CDD:276809 8/31 (26%)
TTC13NP_078801.3 TPR_11 119..>418 CDD:330823 60/247 (24%)
TPR 1 143..176
TPR repeat 147..171 CDD:276809
TPR repeat 179..210 CDD:276809
TPR 2 216..248 7/31 (23%)
TPR repeat 216..244 CDD:276809 5/27 (19%)
TPR 3 249..282 9/32 (28%)
TPR repeat 249..277 CDD:276809 8/27 (30%)
TPR repeat 282..312 CDD:276809 8/29 (28%)
TPR 4 284..316 8/31 (26%)
TPR 5 317..350 9/66 (14%)
TPR repeat 317..344 CDD:276809 6/26 (23%)
TPR repeat 351..379 CDD:276809 10/30 (33%)
TPR 6 352..384 12/34 (35%)
TPR repeat 385..412 CDD:276809 7/30 (23%)
TPR 7 386..418 7/29 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165149863
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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