DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5038 and Dnaaf4

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_080590.3 Gene:Dnaaf4 / 67685 MGIID:1914935 Length:420 Species:Mus musculus


Alignment Length:196 Identity:34/196 - (17%)
Similarity:60/196 - (30%) Gaps:75/196 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   417 VRTRQRATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESAL 481
            ::..:|..|||.                           |.||...|.::|..|::.|       
Mouse   281 LKEEERNPDWLK---------------------------DKGNKLFATENYLAAVDAY------- 311

  Fly   482 MNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKY----- 541
                                .||::.....|..::|............||:....|||:.     
Mouse   312 --------------------NLAIRLNCKIPLLYLNRAACHLKLKNLHKAIEDSSKALELLTPPV 356

  Fly   542 --RANFAV-CYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRIS 603
              .||..: .:...|..:.:.:.|.|.|..::.|:.::|.             |..:|:||.:|.
Mouse   357 ADNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPA-------------NTVVQNDAEKIR 408

  Fly   604 N 604
            |
Mouse   409 N 409

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 30/171 (18%)
TPR_1 444..477 CDD:278916 7/32 (22%)
TPR repeat 444..472 CDD:276809 6/27 (22%)
TPR_17 466..499 CDD:290167 3/32 (9%)
TPR repeat 480..506 CDD:276809 2/25 (8%)
TPR repeat 511..541 CDD:276809 7/29 (24%)
TPR_1 512..545 CDD:278916 8/39 (21%)
TPR_1 546..577 CDD:278916 5/31 (16%)
TPR repeat 546..574 CDD:276809 5/28 (18%)
TPR repeat 580..608 CDD:276809 6/25 (24%)
TPR repeat 614..642 CDD:276809
TPR repeat 647..677 CDD:276809
Dnaaf4NP_080590.3 Mediates interaction with ESR1 and STUB1. /evidence=ECO:0000250 7..103
p23_DYX1C1_like 10..87 CDD:107226
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 164..212
TPR_11 287..351 CDD:290150 19/117 (16%)
TPR 1 288..321 12/86 (14%)
TPR repeat 288..316 CDD:276809 12/81 (15%)
TPR repeat 321..351 CDD:276809 7/29 (24%)
TPR 2 322..355 7/32 (22%)
TPR_1 322..351 CDD:278916 7/28 (25%)
TPR_12 324..396 CDD:290160 13/71 (18%)
TPR repeat 362..392 CDD:276809 5/29 (17%)
TPR 3 364..397 6/45 (13%)
TPR_1 365..397 CDD:278916 6/44 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.