DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5038 and kdm6a

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:XP_005167851.1 Gene:kdm6a / 569277 ZFINID:ZDB-GENE-081105-56 Length:1452 Species:Danio rerio


Alignment Length:307 Identity:60/307 - (19%)
Similarity:106/307 - (34%) Gaps:98/307 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   379 FCLLSIYGFL----------YWYDSSTENTHWRTALRILLMLLFSVMMVRTRQRATDWLNEEQLF 433
            ||.|..:..|          |....|.::.:|:.|     ..|:.:.:|.....|..|       
Zfish    98 FCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNA-----AFLYGLGLVYFHYNAFRW------- 150

  Fly   434 KSALQVCPDNA-------------------------KVHYNIA---RLATDMGNNTKAFQ----- 465
              |:|:.|.:|                         ::|..:.   ::.||..::.|.||     
Zfish   151 --AVQLTPSDAQSGQRRAIKAFQEVLYIDPCFSRAKEIHLRLGLMFKVNTDYESSLKHFQLALID 213

  Fly   466 -------------HYHRAIELYPNYESA---------------------LMNLGNLYREHGQL-- 494
                         |.....|:...|..|                     |..||.::....||  
Zfish   214 STPCTLSKAEIQFHIAHVYEIQKKYRIAKEAYESLLQTENLPAQVKATTLQQLGWMHHTVEQLGD 278

  Fly   495 -----STAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGN 554
                 |.|.:.::.:|:|.|....:|..||...|:.||...|..||.:::......|..:.::|.
Zfish   279 KANKNSYAIQCLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGV 343

  Fly   555 LYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALR 601
            ||.:|.:..:||..:..||.|:.....||.::.|:.::.....||::
Zfish   344 LYQQQNQPMDALQAYICAVQLDHSHAAAWMDLGTLYESCNQPQDAIK 390

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 45/234 (19%)
TPR_1 444..477 CDD:278916 9/78 (12%)
TPR repeat 444..472 CDD:276809 8/73 (11%)
TPR_17 466..499 CDD:290167 11/60 (18%)
TPR repeat 480..506 CDD:276809 8/53 (15%)
TPR repeat 511..541 CDD:276809 9/29 (31%)
TPR_1 512..545 CDD:278916 9/32 (28%)
TPR_1 546..577 CDD:278916 10/30 (33%)
TPR repeat 546..574 CDD:276809 8/27 (30%)
TPR repeat 580..608 CDD:276809 5/22 (23%)
TPR repeat 614..642 CDD:276809
TPR repeat 647..677 CDD:276809
kdm6aXP_005167851.1 TPR 74..332 CDD:223533 45/247 (18%)
TPR repeat 95..123 CDD:276809 5/24 (21%)
TPR repeat 131..176 CDD:276809 9/58 (16%)
TPR repeat 181..211 CDD:276809 6/29 (21%)
TPR repeat 222..250 CDD:276809 4/27 (15%)
TPR repeat 260..295 CDD:276809 7/34 (21%)
TPR_17 289..320 CDD:290167 9/30 (30%)
TPR_11 302..365 CDD:290150 18/62 (29%)
TPR repeat 302..329 CDD:276809 9/26 (35%)
TPR repeat 334..364 CDD:276809 9/29 (31%)
TPR_1 335..368 CDD:278916 10/32 (31%)
TPR repeat 369..395 CDD:276809 5/22 (23%)
SSDP 572..852 CDD:282372
JmjC 1149..1213 CDD:214721
JmjC 1183..1291 CDD:202224
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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