DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5038 and ifit12

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_001177394.1 Gene:ifit12 / 567504 ZFINID:ZDB-GENE-120406-2 Length:474 Species:Danio rerio


Alignment Length:291 Identity:58/291 - (19%)
Similarity:121/291 - (41%) Gaps:70/291 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   431 QLFKSALQVCPDNAK--VHYNIARLATDMGN------NTKAFQHYHRAIELYPNYE--SALMNLG 485
            ::|:.|:::.|.|::  ..|.||...|:..|      .|.|.:...:||:|.|:.:  ..::.:.
Zfish   162 EVFQKAVELDPTNSEWNAGYAIALYRTENFNPPPCTVETPAIKQLRQAIDLNPDDDVLRVILGIK 226

  Fly   486 NLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKY--RANF--- 545
            .|....|.::.:|:.:..||...|..|.....:|:....||..|:::...:|||:.  ::.|   
Zfish   227 LLNCSKGLMNESEQLVEKALNQSPEHPHVIRYVGMFLRDQGSVDRSIEILKKALQRSPKSGFICH 291

  Fly   546 --AVCYYNMG-NLYLEQKRYAE-------ALHHWQHAVALNPRQPKAWANILTMLDNKGLQ---- 596
              |:||.... ||..|::|..|       ::::.:.|.:|.|       :.::.:...|||    
Zfish   292 QLAMCYKTKKINLCKEKRRKVEVDEARDQSIYYLEEATSLIP-------SFISAVCQLGLQYGDR 349

  Fly   597 ----------DDALRISNQALQHLPNDVSILFIRANVLGK------LKHYTEAEA---------- 635
                      |.|.::..:..:|| ..|.:.:.:......      ::||.:...          
Zfish   350 RDLLKAEEQFDKAFKLVKEKNEHL-QSVHLSYAQFQQYSNRREDLAIEHYEKCLTMNPHTPDGNR 413

  Fly   636 -------IYKRVIELEPHNTLYHTNLGVLYH 659
                   |.|:.::|.|::...:..||::|:
Zfish   414 SAQKLCNIAKKNLKLNPNDWKANEILGLVYN 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 55/280 (20%)
TPR_1 444..477 CDD:278916 11/40 (28%)
TPR repeat 444..472 CDD:276809 8/35 (23%)
TPR_17 466..499 CDD:290167 6/34 (18%)
TPR repeat 480..506 CDD:276809 4/25 (16%)
TPR repeat 511..541 CDD:276809 8/29 (28%)
TPR_1 512..545 CDD:278916 8/34 (24%)
TPR_1 546..577 CDD:278916 10/38 (26%)
TPR repeat 546..574 CDD:276809 9/35 (26%)
TPR repeat 580..608 CDD:276809 5/41 (12%)
TPR repeat 614..642 CDD:276809 5/50 (10%)
TPR repeat 647..677 CDD:276809 3/13 (23%)
ifit12NP_001177394.1 TPR repeat 55..83 CDD:276809
TPR repeat 88..127 CDD:276809
TPR_12 97..172 CDD:290160 2/9 (22%)
TPR_2 139..174 CDD:285020 3/11 (27%)
TPR repeat 139..169 CDD:276809 2/6 (33%)
TPR repeat 174..212 CDD:276809 10/37 (27%)
TPR repeat 217..246 CDD:276809 3/28 (11%)
TPR repeat 286..331 CDD:276809 10/44 (23%)
TPR repeat 336..364 CDD:276809 5/27 (19%)
TPR repeat 374..402 CDD:276809 3/27 (11%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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