DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5038 and Spag1

DIOPT Version :9

Sequence 1:	NP_650451.1	Gene:	CG5038 / 41867	FlyBaseID:	FBgn0038324	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_651514.1	Gene:	Spag1 / 43239	FlyBaseID:	FBgn0039463	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	52/247 - (21%)
Similarity:	91/247 - (36%)	Gaps:	84/247 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   420 RQRATDW----------------LNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYH 468
            |.::||:                ||||:..:...::..:::|      .:.||...:.:.
  Fly   154 RIKSTDYRKWDKYDPDEEILRMDLNEERDQEQREKIISNHSK------SVTTDKLQSERD----- 207

  Fly   469 RAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALA 533
               .||...::.|.||..|.:|    ..||   |..|:...:|.|.            :|:.|:.
  Fly   208 ---SLYERLQAQLKNLSQLEKE----QFAE---RHRLRGNESFKAK------------EYENAIE 250

  Fly   534 SYEKALKYRANFAV-CYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQD 597
            .|..::.|....|| .|.|....:|:.|:|..|:...|..:.::|...||
  Fly   251 EYNCSIIYDPENAVHAYNNRAVAHLKLKKYFSAISDCQACLQIDPMNIKA--------------- 300

  Fly   598 DALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTL 649
             .||:   |..|            |..||   :.|:..:||::::.||.|.:
  Fly   301 -HLRM---AEAH------------NAEGK---HLESLNVYKKLLDFEPDNAI 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5038	NP_650451.1	DUF1736	258..331	CDD:285594
		TPR	442..701	CDD:223533	45/209 (22%)
		TPR_1	444..477	CDD:278916	5/32 (16%)
		TPR repeat	444..472	CDD:276809	3/27 (11%)
		TPR_17	466..499	CDD:290167	8/32 (25%)
		TPR repeat	480..506	CDD:276809	8/25 (32%)
		TPR repeat	511..541	CDD:276809	5/29 (17%)
		TPR_1	512..545	CDD:278916	5/32 (16%)
		TPR_1	546..577	CDD:278916	9/31 (29%)
		TPR repeat	546..574	CDD:276809	9/28 (32%)
		TPR repeat	580..608	CDD:276809	5/27 (19%)
		TPR repeat	614..642	CDD:276809	6/27 (22%)
		TPR repeat	647..677	CDD:276809	1/3 (33%)
Spag1	NP_651514.1	TPR_11	229..295	CDD:290150	19/80 (24%)
		TPR repeat	229..257	CDD:276809	9/42 (21%)
		TPR repeat	262..293	CDD:276809	9/30 (30%)
		TPR_11	266..329	CDD:290150	20/96 (21%)
		TPR	266..297	CDD:197478	8/30 (27%)
		TPR repeat	298..326	CDD:276809	12/61 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900