DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5038 and Spag1

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_001012116.1 Gene:Spag1 / 315033 RGDID:1310702 Length:893 Species:Rattus norvegicus


Alignment Length:255 Identity:49/255 - (19%)
Similarity:81/255 - (31%) Gaps:83/255 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   442 DNAKVHY-NIARLATDMGNNTKAFQHYHRAIELYP-----------------NYESALMNLGNLY 488
            |...:.| |.|......||.....|...||:||.|                 .|.||.::...:.
  Rat   468 DELSILYSNRAACYLKEGNCRGCIQDCDRALELQPFAVKPLLRRAMAYETLEQYRSAYVDYITVL 532

  Fly   489 REHGQLSTAEEYI---------------RLALQAYPAFPAA-----W------------------ 515
            :...::..|.:.:               |..|...||.||:     |                  
  Rat   533 KIDCRIQLASDSVNRITRILTELDGPKWRERLPPIPAVPASEPLRVWHPAAETPDQDPCPNSCTP 597

  Fly   516 ------MNLGIVQSA-----QGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHW 569
                  |...:.:..     ...|..|::.|.:.||..:.....|.|....||:..::.||....
  Rat   598 TITDEKMFQALKEEGNQLVKDKNYKDAISKYNECLKINSKACAIYTNRALCYLKLGQFEEAKLDC 662

  Fly   570 QHAVALNPRQPKAWANILTMLDNKGLQDDALRI------------SNQALQHL--PNDVS 615
            ..|:.::.:..|  |:....|..|||::...|:            |::|.:||  .||.:
  Rat   663 DKALQIDSKNVK--ASYRLELAQKGLENCRERVADPSQVVLLSPDSSEAARHLDTKNDTA 720

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 49/255 (19%)
TPR_1 444..477 CDD:278916 11/50 (22%)
TPR repeat 444..472 CDD:276809 8/28 (29%)
TPR_17 466..499 CDD:290167 9/49 (18%)
TPR repeat 480..506 CDD:276809 3/40 (8%)
TPR repeat 511..541 CDD:276809 8/63 (13%)
TPR_1 512..545 CDD:278916 9/66 (14%)
TPR_1 546..577 CDD:278916 7/30 (23%)
TPR repeat 546..574 CDD:276809 7/27 (26%)
TPR repeat 580..608 CDD:276809 9/39 (23%)
TPR repeat 614..642 CDD:276809 0/2 (0%)
TPR repeat 647..677 CDD:276809
Spag1NP_001012116.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 112..155
3a0801s09 141..>303 CDD:273380
TPR 1 213..246
TPR repeat 217..241 CDD:276809
TPR repeat 246..275 CDD:276809
TPR 2 247..279
TPR 3 280..313
TPR repeat 280..308 CDD:276809
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 324..344
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 349..368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 373..437
TPR 4 429..463
3a0801s09 <432..>569 CDD:273380 18/100 (18%)
TPR repeat 432..458 CDD:276809
TPR repeat 466..500 CDD:276809 9/31 (29%)
TPR 5 471..504 11/32 (34%)
TPR repeat 505..533 CDD:276809 3/27 (11%)
TPR 6 506..538 3/31 (10%)
3a0801s09 569..>695 CDD:273380 24/127 (19%)
TPR 7 605..638 5/32 (16%)
TPR repeat 606..633 CDD:276809 3/26 (12%)
TPR repeat 638..668 CDD:276809 7/29 (24%)
TPR 8 639..672 7/32 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 704..756 6/17 (35%)
RPAP3_C 769..858 CDD:404718
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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