| Sequence 1: | NP_650451.1 | Gene: | Tmtc4 / 41867 | FlyBaseID: | FBgn0038324 | Length: | 705 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_570722.2 | Gene: | DNAAF4 / 161582 | HGNCID: | 21493 | Length: | 420 | Species: | Homo sapiens |
| Alignment Length: | 249 | Identity: | 53/249 - (21%) |
|---|---|---|---|
| Similarity: | 99/249 - (39%) | Gaps: | 53/249 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 429 EEQLFKSALQVCPDNAKVHY-----NIA--RLATDMGNNTKAFQHYHRAIELYPNYESALMNLGN 486
Fly 487 L------------YREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKAL 539
Fly 540 KYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWAN-ILTMLDNKGLQDDALRIS 603
Fly 604 NQALQHL---PNDVSILFIRANV-----LGKLKHYTEAEAIYKRVIELEPHNTL 649 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Tmtc4 | NP_650451.1 | TMTC_DUF1736 | 258..331 | CDD:462468 | |
| LapB | 431..675 | CDD:442196 | 51/247 (21%) | ||
| TPR repeat | 444..472 | CDD:276809 | 8/34 (24%) | ||
| TPR repeat | 480..506 | CDD:276809 | 7/37 (19%) | ||
| TPR repeat | 511..541 | CDD:276809 | 5/29 (17%) | ||
| TPR repeat | 546..574 | CDD:276809 | 5/27 (19%) | ||
| TPR repeat | 580..608 | CDD:276809 | 8/28 (29%) | ||
| TPR repeat | 614..642 | CDD:276809 | 6/32 (19%) | ||
| TPR repeat | 647..677 | CDD:276809 | 1/3 (33%) | ||
| DNAAF4 | NP_570722.2 | Mediates interaction with ESR1 and STUB1. /evidence=ECO:0000269|PubMed:19423554 | 7..103 | ||
| p23_DYX1C1_like | 10..87 | CDD:107226 | |||
| TPR 1 | 290..323 | 8/45 (18%) | |||
| TPR repeat | 290..318 | CDD:276809 | 6/40 (15%) | ||
| NlpI | <297..>399 | CDD:443815 | 25/102 (25%) | ||
| TPR repeat | 323..353 | CDD:276809 | 9/30 (30%) | ||
| TPR 2 | 324..357 | 10/33 (30%) | |||
| TPR repeat | 364..394 | CDD:276809 | 6/29 (21%) | ||
| TPR 3 | 366..399 | 7/32 (22%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||