DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5038 and Ifit2

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_001342191.1 Gene:Ifit2 / 15958 MGIID:99449 Length:470 Species:Mus musculus


Alignment Length:200 Identity:41/200 - (20%)
Similarity:80/200 - (40%) Gaps:27/200 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   480 ALMNLGN---LYREHGQLSTAEEYIRLALQAYPAF--------PA-----AWMNLGIVQSAQGK- 527
            :|:..||   :|...||.|.|:.|:....|....|        ||     .|..|...::...: 
Mouse    93 SLVTWGNYAWVYYHMGQFSKAQAYLDKVKQVCKKFSSPYRIENPALDCEEGWARLKCTKNQNERV 157

  Fly   528 ---YDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTM 589
               :.|||....|..::.:.:|:..|.:.:  ...:.|  .:...:.|:.|:|  ...:..:|..
Mouse   158 KVCFQKALEKDPKNPEFTSGWAIANYRLDD--WPARNY--CIDSLEQAIQLSP--DNTYVKVLLA 216

  Fly   590 LDNKGL-QDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTN 653
            |....: ::.|:.:..:||:..|:.:..|...|....|:.....|..:.::.:|..|:|...|..
Mouse   217 LKLDAVHKNQAMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYY 281

  Fly   654 LGVLY 658
            :|..|
Mouse   282 MGCCY 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 40/199 (20%)
TPR_1 444..477 CDD:278916
TPR repeat 444..472 CDD:276809
TPR_17 466..499 CDD:290167 8/21 (38%)
TPR repeat 480..506 CDD:276809 9/28 (32%)
TPR repeat 511..541 CDD:276809 9/46 (20%)
TPR_1 512..545 CDD:278916 8/41 (20%)
TPR_1 546..577 CDD:278916 5/30 (17%)
TPR repeat 546..574 CDD:276809 4/27 (15%)
TPR repeat 580..608 CDD:276809 4/28 (14%)
TPR repeat 614..642 CDD:276809 4/27 (15%)
TPR repeat 647..677 CDD:276809 3/11 (27%)
Ifit2NP_001342191.1 TPR 1 51..89
TPR 2 90..135 11/41 (27%)
TPR repeat 96..122 CDD:276809 8/25 (32%)
TPR repeat 127..167 CDD:276809 8/39 (21%)
TPR 3 136..171 7/34 (21%)
PEP_TPR_lipo <145..359 CDD:274350 26/147 (18%)
TPR 4 172..208 6/41 (15%)
TPR 5 242..275 6/32 (19%)
TPR repeat 242..270 CDD:276809 4/27 (15%)
TPR repeat 275..325 CDD:276809 3/11 (27%)
TPR 6 276..331 2/10 (20%)
TPR repeat 330..358 CDD:276809
TPR 7 332..362
TPR 8 363..401
TPR 9 402..443
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 439..470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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