DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5038 and Ifit1bl2

DIOPT Version :9

Sequence 1:	NP_650451.1	Gene:	CG5038 / 41867	FlyBaseID:	FBgn0038324	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_001349059.1	Gene:	Ifit1bl2 / 112419	MGIID:	2148249	Length:	466	Species:	Mus musculus

Alignment Length:	305	Identity:	66/305 - (21%)
Similarity:	111/305 - (36%)	Gaps:	109/305 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 VRTRQRATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESAL 481
            :::.:.|...:..|||.|.:                ||| .||  .|:.||||
Mouse    80 LQSLKEAEALIQSEQLSKRS----------------LAT-WGN--CAWLHYHR------------ 113

  Fly   482 MNLGNLYREHGQLSTAEEYIRLALQAYPAFPA---------------AWMNLGIVQSAQGKYDKA 531
                      |.|:.|:.|:....:....|.:               .|   .:.:.....|.:|
Mouse   114 ----------GSLAEAQVYLDKVEKVCKEFSSPFRYRLECAEMDCEEGW---ALRKCGSQNYTRA 165

  Fly   532 LASYEKALK-------YRANFAVCYYNM----GNLYLEQKRYAEALHHWQHAVALNPRQPKAWAN 585
            :|.:|:|||       |.|.:|...|::    ||          :|...:.||::.|..|  :..
Mouse   166 MACFERALKVEPENPEYNAGYADVAYHLDYYDGN----------SLQPLKKAVSVKPEDP--YLK 218

  Fly   586 ILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKL-KHY------TEAEAIYKRVIEL 643
            :|..|.   |||  ||.:::|.:|:......:..:.|:.|.: |.|      .||....|:.:|.
Mouse   219 VLLALK---LQD--LRKTDEAEKHIKEATLTISSQNNIFGYVAKFYRRKGCVEEALGFLKKALET 278

  Fly   644 EPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAARATTAREN 688
            :|.:...|..:|:.:    |||           ....:..|:|||
Mouse   279 KPSSPYLHFQIGLCH----KTQ-----------FFQMKKATSREN 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5038	NP_650451.1	DUF1736	258..331	CDD:285594
		TPR	442..701	CDD:223533	61/280 (22%)
		TPR_1	444..477	CDD:278916	10/32 (31%)
		TPR repeat	444..472	CDD:276809	10/27 (37%)
		TPR_17	466..499	CDD:290167	7/32 (22%)
		TPR repeat	480..506	CDD:276809	4/25 (16%)
		TPR repeat	511..541	CDD:276809	9/51 (18%)
		TPR_1	512..545	CDD:278916	10/54 (19%)
		TPR_1	546..577	CDD:278916	7/34 (21%)
		TPR repeat	546..574	CDD:276809	6/31 (19%)
		TPR repeat	580..608	CDD:276809	9/27 (33%)
		TPR repeat	614..642	CDD:276809	7/34 (21%)
		TPR repeat	647..677	CDD:276809	5/29 (17%)
Ifit1bl2	NP_001349059.1	TPR_11	<63..>353	CDD:330823	66/305 (22%)
		TPR repeat	63..94	CDD:276809	1/13 (8%)
		TPR repeat	99..129	CDD:276809	14/70 (20%)
		TPR repeat	144..174	CDD:276809	6/32 (19%)
		TPR repeat	179..210	CDD:276809	9/40 (23%)
		TPR repeat	215..241	CDD:276809	10/32 (31%)
		TPR repeat	282..329	CDD:276809	9/42 (21%)
		TPR_11	<324..>458	CDD:330823
		TPR repeat	334..362	CDD:276809
		TPR repeat	372..401	CDD:276809
		TPR repeat	429..457	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810