DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5038 and TOMM34

DIOPT Version :9

Sequence 1:NP_650451.1 Gene:CG5038 / 41867 FlyBaseID:FBgn0038324 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_006800.2 Gene:TOMM34 / 10953 HGNCID:15746 Length:309 Species:Homo sapiens


Alignment Length:255 Identity:50/255 - (19%)
Similarity:83/255 - (32%) Gaps:78/255 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   435 SALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEE 499
            |||.:.|.:.|.....|.....:.....|:..|...:::..|..||:..:..:.|.... |...|
Human    76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMD-SLGPE 139

  Fly   500 YIRLALQAYPAFPAA----WMNL--------------------------GIVQSA---------- 524
            : ||.|.:.|..|.:    |.:|                          |.|:.|          
Human   140 W-RLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNEL 203

  Fly   525 --QGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANIL 587
              :|.:.||:..|.::|......:..|.|....||..|:|.||:.....|:.|:.:..||:    
Human   204 VKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAF---- 264

  Fly   588 TMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHN 647
                                          :.||.....||.|..:.|....::::||.|
Human   265 ------------------------------YRRAQAHKALKDYKSSFADISNLLQIEPRN 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5038NP_650451.1 DUF1736 258..331 CDD:285594
TPR 442..701 CDD:223533 46/248 (19%)
TPR_1 444..477 CDD:278916 4/32 (13%)
TPR repeat 444..472 CDD:276809 4/27 (15%)
TPR_17 466..499 CDD:290167 6/32 (19%)
TPR repeat 480..506 CDD:276809 6/25 (24%)
TPR repeat 511..541 CDD:276809 11/71 (15%)
TPR_1 512..545 CDD:278916 11/74 (15%)
TPR_1 546..577 CDD:278916 10/30 (33%)
TPR repeat 546..574 CDD:276809 9/27 (33%)
TPR repeat 580..608 CDD:276809 2/27 (7%)
TPR repeat 614..642 CDD:276809 6/27 (22%)
TPR repeat 647..677 CDD:276809 1/1 (100%)
TOMM34NP_006800.2 TPR 1 9..42
TPR repeat 9..37 CDD:276809
PLN03088 <12..>294 CDD:330826 49/253 (19%)
TPR repeat 50..80 CDD:276809 3/3 (100%)
TPR 2 51..84 4/7 (57%)
TPR repeat 85..113 CDD:276809 4/27 (15%)
TPR 3 86..118 4/31 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..189 1/27 (4%)
TPR 4 193..226 6/32 (19%)
TPR repeat 193..221 CDD:276809 5/27 (19%)
TPR repeat 226..256 CDD:276809 9/29 (31%)
TPR 5 227..260 10/32 (31%)
TPR repeat 261..289 CDD:276809 8/61 (13%)
TPR 6 262..294 10/65 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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