DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Surf4 and surf4l

DIOPT Version :9

Sequence 1:	NP_477222.1	Gene:	Surf4 / 41864	FlyBaseID:	FBgn0019925	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001002470.1	Gene:	surf4l / 436743	ZFINID:	ZDB-GENE-040718-172	Length:	269	Species:	Danio rerio

Alignment Length:	267	Identity:	164/267 - (61%)
Similarity:	216/267 - (80%)	Gaps:	0/267 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PNEYIAKTEDVAEQVIKRGKNVLPTVARLCLIATFFEDGLRMYIQWNEQREYMDMSWGCGKFLAT 68
            ||:.::..||||:|.::..|..||.:||||||:||.|||:||:.||:||:||::.:|.||.||||
Zfish     3 PNDLMSNAEDVADQFLRVTKQYLPHIARLCLISTFLEDGIRMWFQWSEQKEYIETTWSCGFFLAT 67

  Fly    69 VFVLVNLLGQLGGCGMVMARFKVDIAVGLLFFIVVLQTVAYSILWDFQFLLRNFALIGALLLVLA 133
            :|||:|||||||||.::::|..|..|...||.|:.|||||||||||.:||:||.||.|.|||:||
Zfish    68 LFVLINLLGQLGGCILILSRNFVQYACFGLFAIIALQTVAYSILWDPKFLMRNLALGGGLLLLLA 132

  Fly   134 EARIEGRSLFAGVPSMGENKPKNFMQLAGRILLAFMFITLIRFELSVWQVIQDIIGSILMVLVVL 198
            |:|.||||:|||||:|.|:.||.:|||.||:||..||:||:.|:.|...::|:::|:.|:|||.:
Zfish   133 ESRSEGRSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDTSFLSILQNLVGTALIVLVAI 197

  Fly   199 GYKTKLSALILVALLTILNLYHNAWWTIPSYKPLRDFLKYDFFQTLSVIGGLLMIVSLGPGGVSM 263
            |:||||:||.||..|..:|:|.||:||||:|||:.||||||||||.|||||||:||:||||||||
Zfish   198 GFKTKLAALTLVIWLLAINVYFNAFWTIPAYKPMHDFLKYDFFQTTSVIGGLLLIVALGPGGVSM 262

  Fly   264 DEHKKKW 270
            ||.||:|
Zfish   263 DEKKKEW 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Surf4	NP_477222.1	SURF4	5..270	CDD:111019	162/264 (61%)
surf4l	NP_001002470.1	SURF4	4..269	CDD:111019	162/264 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576590
Domainoid	1	1.000	345	1.000	Domainoid score	I1025
eggNOG	1	0.900	-	-		E1_COG2259
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	347	1.000	Inparanoid score	I2276
OMA	1	1.010	-	-		QHG51950
OrthoDB	1	1.010	-	-		D1272733at2759
OrthoFinder	1	1.000	-	-		FOG0003735
OrthoInspector	1	1.000	-	-		otm25541
orthoMCL	1	0.900	-	-		OOG6_104535
Panther	1	1.100	-	-	O	PTHR23427
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1415
SonicParanoid	1	1.000	-	-		X2591
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800