Protein Alignment SerRS-m and SARS2

DIOPT Version :10

• Sequence 1: NP_524365.1
• Gene: SerRS-m / 41862
• FlyBaseID: FBgn0021750
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_001139373.1
• Gene: SARS2 / 54938
• HGNCID: 17697
• Length: 520
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 160/434 - (36%)
• Similarity: 244/434 - (56%)
• Gaps: 62/434 - (14%)

  Fly    20 RSHDAKAVEAPIHRPVPTSAQLDELERNV-VVRHHKNNV-PLIRSLIQELDAGDQHKLR------ 76
            ||.|..|:       :.|..:|.:|:..: .:...|..| ..:|:|:...|:|:..::|
Human    82 RSADLPAI-------ISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQVRLDPGAG 139

  Fly    77 ------------QL----QAELEQ--------LPNATHPRLRDYGEEPRELAQYVHR-------Q 110
                        ||    :|:||:        |||.|||.: ..|:|.:  |:.:|.       .
Human   140 SIFGPTFLPFPGQLSLLVEAQLEEQFYLQALKLPNQTHPDV-PVGDESQ--ARVLHMVGDKPVFS 201

  Fly   111 LTPQSRLKEFSELARALNLYRMDHLGNYTGHKSYYLTGQLATLEQAIIQYALQAVTEHGFKLISV 175
            ..|:..|    |:...|::.|...|.:.:||:||||.|..|.|:..::.:....:...||..::|
Human   202 FQPRGHL----EIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMTV 262

  Fly   176 PDILPKEVIESCGMRTEGERTQVYKLDTGEC----LSGTSEMALAGFFANKLLSEDQLPLKVTAV 236
            ||:|...|.|.|||......:|:|.:|....    |:||:|:.|||:|.:..::...||:::...
Human   263 PDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTAEVGLAGYFMDHTVAFRDLPVRMVCS 327

  Fly   237 SRCYRAETSGLQEEKGIYRVHQFNKVEMFAICTE--EQSEAELEEFKNIEVDLFRRLGLNFRLLD 299
            |.||||||:..||.:|:||||.|.|||||.:...  |||...||||.::::::...|||:||:||
Human   328 STCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLD 392

  Fly   300 MPPCELGAPAYQKYDIEAWMPGRQMWGEISSCSNCTDYQARRLGIRYRRSADGQILHAHTINGTA 364
            ||..|||.|||:|:|||||||||..:||::|.|||||:|:|||.|.::..| |::..|||:|.||
Human   393 MPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMFQTEA-GELQFAHTVNATA 456

  Fly   365 TAIPRLLIALLESYQKEDG-IEIPAVLRPFMDNQELITRNKRIP 407
            .|:||||||||||.|::|| :.:|..|:.:: ..:.||....:|
Human   457 CAVPRLLIALLESNQQKDGSVLVPPALQSYL-GTDRITAPTHVP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerRS-m	NP_524365.1	class_II_aaRS-like_core	100..394	CDD:444800	130/307 (42%)
SARS2	NP_001139373.1	Prefoldin	94..>138	CDD:471851	9/43 (21%)
		coiled coil	95..122	CDD:467470	6/26 (23%)
		SerRS_core	187..487	CDD:238393	130/306 (42%)