DRSC/TRiP Functional Genomics Resources

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Protein Alignment SerRS-m and sars1

DIOPT Version :9

Sequence 1:NP_001262599.1 Gene:SerRS-m / 41862 FlyBaseID:FBgn0021750 Length:417 Species:Drosophila melanogaster
Sequence 2:NP_001003882.1 Gene:sars1 / 445405 ZFINID:ZDB-GENE-040831-1 Length:515 Species:Danio rerio


Alignment Length:410 Identity:123/410 - (30%)
Similarity:208/410 - (50%) Gaps:45/410 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 VPTSAQ-LDELERNVVVRHHKNNVPLIRSLIQE-LDAGDQHKLRQLQAE----LEQLPNATHPRL 93
            :|..|| |:.|....:.......:..:|.|:.| :...|..:|: |:||    |.::.|..||.:
Zfish    80 LPEEAQNLEALTAETLSPLTVTQIKKVRVLVDEAVQKTDSDRLK-LEAERFEYLREIGNLLHPSV 143

  Fly    94 RDYGEEPRELAQYVHRQLTPQSRLKEFS--ELARALNLYRMDHLGNYTGHKSYYLTGQLATLEQA 156
            ....:|..:  ..|.|.....:..|::|  :|...::.|..:......|.:.|:|.|.|..||||
Zfish   144 PISNDEDAD--NKVERTWGDCTVQKKYSHVDLVVMVDGYEGEKGAIVAGSRGYFLKGPLVFLEQA 206

  Fly   157 IIQYALQAVTEHGFKLISVPDILPKEVIESCGMRTEGERTQVYKL--------DTG----ECLSG 209
            :|.|||:.:....:.|:..|..:.|||::.....::.:. ::||:        |..    :.|..
Zfish   207 LINYALRILYSKNYNLLYTPFFMRKEVMQEVAQLSQFDE-ELYKVIGKGSEKSDDNTVDEKYLIA 270

  Fly   210 TSEMALAGFFANKLLSEDQLPLKVTAVSRCYRAET-SGLQEEKGIYRVHQFNKVEMFAICT--EE 271
            |||..:|.|..::.|..::||::...:|.|:|.|. |..::.:||:|||||.|:|.|...:  :.
Zfish   271 TSEQPIAAFLRDEWLKPEELPIRYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYASPHDG 335

  Fly   272 QSEAELEEFKNIEVDLFRRLGLNFRLLDMPPCELGAPAYQKYDIEAWMPGRQMWGEISSCSNCTD 336
            :|....:|........::.||:.:|::::....|...|.:|.|:|||.||.|.:.|:.|||||||
Zfish   336 KSWEMFDEMIGTAESFYQTLGIPYRIVNIVSGALNHAASKKLDLEAWFPGSQAFRELVSCSNCTD 400

  Fly   337 YQARRLGIRY---RRSADGQILHAHTINGTATAIPRLLIALLESYQKEDGIEIPAVLRPFMDNQE 398
            ||||||.|||   ::..| :....|.:|.|..|..|::.|:||::|.|:||.:|..|:.||    
Zfish   401 YQARRLRIRYGQTKKMMD-KAEFVHMLNATMCATTRVICAILENFQTEEGIIVPEPLKAFM---- 460

  Fly   399 LITRNKRIPE--TKLVKFIK 416
                    |.  |:::||:|
Zfish   461 --------PPGLTEIIKFVK 472

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SerRS-mNP_001262599.1 SerS 60..404 CDD:223250 113/368 (31%)
class_II_aaRS-like_core 100..394 CDD:294192 98/313 (31%)
sars1NP_001003882.1 SerS 3..475 CDD:333239 123/410 (30%)
Interaction with tRNA. /evidence=ECO:0000250|UniProtKB:P49591 9..61
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 475..515
Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:P49591 482..494
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0172
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D495094at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100275
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.720

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