DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sra-1 and fam49ba

DIOPT Version :9

Sequence 1:	NP_650447.1	Gene:	Sra-1 / 41861	FlyBaseID:	FBgn0038320	Length:	1291	Species:	Drosophila melanogaster
Sequence 2:	NP_956364.2	Gene:	fam49ba / 337591	ZFINID:	ZDB-GENE-030131-9537	Length:	325	Species:	Danio rerio

Alignment Length:	289	Identity:	67/289 - (23%)
Similarity:	114/289 - (39%)	Gaps:	52/289 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 NFDTNFEDRNGFVTGIAKYIE-EATTHANLNVLLDEGQKHAVMLYTWRCCSRAIPQPKSNEQPNR 104
            ||..:||:        ||..| |......:|.:|.|.......|.::.....||.|  :.:.|:.
Zfish    18 NFFLDFEN--------AKPTEAERRVWEEVNGVLREAAIILQDLQSYSGAGEAIRQ--AIQHPSD 72

  Fly   105 VEIYEKTVEVLAPEVNKLLNFMYFQRKAIEAFSGEVKRL----C----HAEKRKDFVSEAYLLTL 161
            ..:.|:....:.|.|.||..|..|..|..:.....::.|    |    |.|:     .:|.....
Zfish    73 ERVQEQAWAAVVPLVGKLKKFYEFSLKLEDTLQNLLEYLTSSRCSPTQHLEQ-----EQALARQF 132

  Fly   162 GKFINMFAVLDELKNMKSSVKNDYSTYRRAAQFLKVMSDSHTLQE--------SQNLSMFLATQN 218
            .:.::.....||||....:::||:|.|||....::::  :.|.:|        :..:|:|.|...
Zfish   133 AEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRII--NQTAEEHNEVDNELANRMSLFYANAT 195

  Fly   219 KIRDTVKDTLEKIVGYE---------DLLSDVVNICVHMFETKMYLT--PEEKHML--VKVMGFG 270
            .:..|:.|...|.|...         |.||.:.::|..|.||..|.:  ..|..:|  ::||...
Zfish   196 PMLKTLSDATTKFVSKHAELPVENTTDCLSTMASVCKVMLETPEYRSRFASEDTVLFCLRVMVGV 260

  Fly   271 LFLMD-----SDACNINKLDQKKKIRLDR 294
            :.|.|     ......:|:|.|..|::.|
Zfish   261 IILYDYVHPAGAFVKSSKIDMKGCIKVLR 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sra-1	NP_650447.1	DUF1394	89..>267	CDD:399855	46/206 (22%)
Sra-1	NP_650447.1	FragX_IP	386..1244	CDD:399175
fam49ba	NP_956364.2	DUF1394	18..320	CDD:284554	67/289 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910