DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sra-1 and Cyria

DIOPT Version :9

Sequence 1:	NP_650447.1	Gene:	Sra-1 / 41861	FlyBaseID:	FBgn0038320	Length:	1291	Species:	Drosophila melanogaster
Sequence 2:	NP_001100188.1	Gene:	Cyria / 298890	RGDID:	1305961	Length:	323	Species:	Rattus norvegicus

Alignment Length:	225	Identity:	52/225 - (23%)
Similarity:	91/225 - (40%)	Gaps:	37/225 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 EQPNRVEIYEKTVEVLAPEVNKLLNFMYFQRKAIEAFSGEVKRL-C-------HAEKRKDFVSEA 156
            :.||.:::.||....:.|.|.:|..|..|..:..:|....::.| |       |.|:.:....|
  Rat    67 QNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQHLEREQALAKE- 130

  Fly   157 YLLTLGKFINMFAVLDELKNMKSSVKNDYSTYRRAAQFLKVMSDSHTLQESQN------LSMFLA 215
                ..:.::.....||||....:::||:|.|||.....::.:....::...|      :|:|.|
  Rat   131 ----FAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYA 191

  Fly   216 TQNKIRDTVKDTLEKIVGYE---------DLLSDVVNICVHMFETKMY---LTPEEKHML-VKVM 267
            ....:..|:.:.....|...         |.||.:.::|..|.||..|   .|.||..|. ::||
  Rat   192 EATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYRSRFTSEETLMFCMRVM 256

  Fly   268 GFGLFLMD-----SDACNINKLDQKKKIRL 292
            ...:.|.|     ...|..:|:|.|..|::
  Rat   257 VGVIILYDHVHPVGAFCKTSKIDMKGCIKV 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sra-1	NP_650447.1	DUF1394	89..>267	CDD:399855	43/193 (22%)
Sra-1	NP_650447.1	FragX_IP	386..1244	CDD:399175
Cyria	NP_001100188.1	DUF1394	17..319	CDD:399855	52/225 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910