DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp39 and FKBP6

DIOPT Version :9

Sequence 1:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_003593.3	Gene:	FKBP6 / 8468	HGNCID:	3722	Length:	327	Species:	Homo sapiens

Alignment Length:	108	Identity:	35/108 - (32%)
Similarity:	54/108 - (50%)	Gaps:	3/108 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 ITGGVKIVDQVV--GKGEEAKQGKRVSVYYIGRLQSNNKTFDS-LLKGKPFKFALGGGEVIKGWD 310
            |:|...::..|:  |.|:.......|.|.|.|.|:..::.||| ..:..|....||....:.|.:
Human    32 ISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGME 96

  Fly   311 VGVAGMKVGGKRVITCPPHMAYGARGAPPKIGPNSTLVFEVEL 353
            :|:..|:.|........|:.|||..|.||.|.||:|::||:||
Human    97 LGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIEL 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	31/93 (33%)
FKBP6	NP_003593.3	FKBP_C	51..140	CDD:306713	30/89 (34%)
		TPR	<164..315	CDD:223533
		TPR 1	171..204
		TPR 2	219..252
		TPR repeat	221..247	CDD:276809
		TPR repeat	252..282	CDD:276809
		TPR 3	253..286
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810