DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp39 and fkbp8

DIOPT Version :9

Sequence 1:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_957178.1	Gene:	fkbp8 / 393858	ZFINID:	ZDB-GENE-040426-1849	Length:	406	Species:	Danio rerio

Alignment Length:	204	Identity:	55/204 - (26%)
Similarity:	93/204 - (45%)	Gaps:	37/204 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 DSD--DSEAEEEQPKAKVAKLSPGASAKKSGKEQNGVAKKEEAKQQQ----------KKKEKPEA 226
            |||  :..|::.: .|.:||.|.|||...|.::...:...|:.....          |||..|
Zfish     3 DSDVVNGSADDHE-VAPLAKKSAGASLLDSREDFEMLEHLEDDVDDDLPPLEDAGGGKKKSSP-- 64

  Fly   227 KKEQPKAKEPAKQQPASKDPRT-------ITGG----VKIVDQVVGKGEEAKQGKRVSVYYIGRL 280
                  ||:|||:..:::.|..       :.|.    .|:::...|.....::|:.|:::....|
Zfish    65 ------AKDPAKEDKSAESPSAEPEEWLDVLGNGQLRKKVLEAGAGPDSRPQKGQNVTIHLKTAL 123

  Fly   281 QSNNKTFDSLLKGKPFKFALGGGEVIKGWDVGVAGMKVGGKRVITCPPHMAYGARG-APPKIGPN 344
             :|....|.|   |...|.||.|:|::..|:.|..|::|.|.:|......||||.| :.|.:.|:
Zfish   124 -TNGTVVDEL---KDLSFTLGDGDVLQALDLTVQLMEMGEKALIEAAAKYAYGALGSSAPAVPPD 184

  Fly   345 STLVFEVEL 353
            :.|:.||:|
Zfish   185 ADLLLEVQL 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	29/93 (31%)
fkbp8	NP_957178.1	FKBP_C	106..194	CDD:278674	29/92 (32%)
		TPR_11	214..296	CDD:290150
		TPR repeat	214..259	CDD:276809
		TPR repeat	265..293	CDD:276809
		TPR_11	266..330	CDD:290150
		TPR repeat	298..328	CDD:276809
		TPR_1	299..332	CDD:278916
		TPR repeat	333..361	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740