DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fkbp39 and Fkbp8

DIOPT Version :9

Sequence 1:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	XP_038950249.1	Gene:	Fkbp8 / 290652	RGDID:	1308670	Length:	410	Species:	Rattus norvegicus

Alignment Length:	214	Identity:	55/214 - (25%)
Similarity:	85/214 - (39%)	Gaps:	50/214 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 LENGEEEDD-DDVDEDNEESGEEDEQDSDDSEAEEEQPKAKVAKLSPGASAKKSGKEQNGVAKKE 212
            ||..|..|. ||.:|:::.||....:|......||.:        .|||.|::.      :|..|
  Rat    21 LEGFEVLDGVDDAEEEDDLSGLPPLEDMGQPTVEEAE--------QPGALAREF------LAATE 71

  Fly   213 EAKQQQKKKEKPEAKKEQPKAKEPAKQQPASKDPRTITGG-----VKIVDQVVGKGEEAKQGKRV 272
                                 .||| ..||.::...|.|.     ..:|....|.....| |:.|
  Rat    72 ---------------------PEPA-PAPAPEEWLDILGNGLLRKKTLVPGPTGSSRPLK-GQVV 113

  Fly   273 SVYYIGRLQSNNKTFDSLLKGKP-FKFALGGGEVIKGWDVGVAGMKVGGKRVITCPPHMAYGARG 336
            :|:....|::..:     ::.:| ..|.||..:||:..|:.|..|.||...::|......||.:|
  Rat   114 TVHLQMSLENGTR-----VQEEPELAFTLGDCDVIQALDLSVPLMHVGETAMVTADSKYCYGPQG 173

  Fly   337 A-PPKIGPNSTLVFEVELK 354
            : .|.|.|::.|..||.||
  Rat   174 SRSPYIPPHAALCLEVTLK 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	26/93 (28%)
Fkbp8	XP_038950249.1	FKBP_C	103..192	CDD:395196	27/94 (29%)
		TPR	<206..336	CDD:223533
		TPR repeat	270..298	CDD:276809
		TPR repeat	303..333	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343333
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930