DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp39 and Fkbp4

DIOPT Version :9

Sequence 1:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_001178792.1	Gene:	Fkbp4 / 260321	RGDID:	628729	Length:	458	Species:	Rattus norvegicus

Alignment Length:	132	Identity:	61/132 - (46%)
Similarity:	75/132 - (56%)	Gaps:	7/132 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 KEQPKAKEPAKQQPASKD-----PRTITGGVKIVDQVVGKGEEAKQGKRVSVYYIGRLQSNNKTF 287
            :|...|:..|:..|...:     |:...|.:|::.:.....|.|..|.||.|:|.|.|....| |
  Rat     4 EEMKVAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETAMIGDRVFVHYTGWLLDGTK-F 67

  Fly   288 DSLLKGK-PFKFALGGGEVIKGWDVGVAGMKVGGKRVITCPPHMAYGARGAPPKIGPNSTLVFEV 351
            ||.|..| .|.|.||.|||||.||:.||.||||....|||.|..|||:.|:||||.||:||||||
  Rat    68 DSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEV 132

  Fly   352 EL 353
            ||
  Rat   133 EL 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	54/93 (58%)
Fkbp4	NP_001178792.1	FKBP_C	43..134	CDD:278674	52/91 (57%)
		Interaction with tubulin	267..400
		TPR_11	274..349	CDD:290150
		TPR repeat	274..301	CDD:276809
		TPR repeat	306..348	CDD:276809
		TPR_1	321..352	CDD:278916
		TPR_11	322..384	CDD:290150
		TPR repeat	353..381	CDD:276809
		TPR_2	354..386	CDD:285020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	423..458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810