DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fkbp39 and fkbp39

DIOPT Version :9

Sequence 1:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_596694.1	Gene:	fkbp39 / 2539812	PomBaseID:	SPBC1347.02	Length:	361	Species:	Schizosaccharomyces pombe

Alignment Length:	380	Identity:	127/380 - (33%)
Similarity:	186/380 - (48%)	Gaps:	89/380 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SFHISGVALDKGQEA----------------------------KLYLAAEKQEYIVATVTK-AIP 57
            |.|::..::|.|:::                            :..|...::|:::.|:.. ::.
pombe    27 SIHLTMASIDAGEKSNKPTTLLVKVRPRIPVEDEDDEELDEQMQELLEESQREFVLCTLKPGSLY 91

  Fly    58 QVALDLNFSKGDRIMFYTAGDASVSLLGYLHDIDSEDDEDDDQMTIENLLNSKAIKNSKKSEDDE 122
            |..|:|..:.||.:.|..:|||::.|.|                   |.|           .|:|
pombe    92 QQPLNLTITPGDEVFFSASGDATIHLSG-------------------NFL-----------VDEE 126

  Fly   123 DENESGEEDEEDTDDDSQIIEEYESFLE--NGEEEDDDDVDEDNEESGEEDEQDSDDSEAEEEQP 185
            |      |:||::|:|..:....|..:|  :|:||.:::.:.::..:.||||.||  :.|::.|.
pombe   127 D------EEEEESDEDYDLSPTEEDLVETVSGDEESEEESESEDNSASEEDELDS--APAKKAQV 183

  Fly   186 KAKVAKLSPGASAKKSGKEQNGVAKKEEAKQQQKKK----EK-------PEAKKEQPKAKEPAKQ 239
            |.|..|.........|.|:.|...:|.|....::||    ||       |.||||:.:|...|
pombe   184 KKKRTKDESEQEEAASPKKNNTKKQKVEGTPVKEKKVAFAEKLEQGPTGPAAKKEKQQASSNA-- 246

  Fly   240 QPASKDPRTITGGVKIVDQVVGKGEEAKQGKRVSVYYIGRLQSNNKTFDSLLKGKPFKFALGGGE 304
             |:|...||:.|||.:.|...|.|..|..||:|.:.|||:|: |.|.||...|||||.|.||.||
pombe   247 -PSSPKTRTLKGGVVVTDVKTGSGASATNGKKVEMRYIGKLE-NGKVFDKNTKGKPFAFILGRGE 309

  Fly   305 VIKGWDVGVAGMKVGGKRVITCPPHMAYGARGAP--PKIGPNSTLVFEVELKAVH 357
            ||:|||||||||:.||:|.||.|..||||.:..|  ||   ||||||||:|..||
pombe   310 VIRGWDVGVAGMQEGGERKITIPAPMAYGNQSIPGIPK---NSTLVFEVKLVRVH 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	55/93 (59%)
fkbp39	NP_596694.1	FkpA	<201..361	CDD:223619	80/166 (48%)
fkbp39	NP_596694.1	FKBP_C	272..358	CDD:278674	54/89 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1783
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	154	1.000	Inparanoid score	I1285
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46988
orthoMCL	1	0.900	-	-		OOG6_104296
Panther	1	1.100	-	-	LDO	PTHR43811
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5708
TreeFam	1	0.960	-	-
	10	9.820