DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and zgc:153968

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001070924.1	Gene:	zgc:153968 / 768292	ZFINID:	ZDB-GENE-061027-211	Length:	301	Species:	Danio rerio

Alignment Length:	293	Identity:	87/293 - (29%)
Similarity:	127/293 - (43%)	Gaps:	56/293 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 SNSLLPLPGQCGNI-LSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASH 173
            |.||..| ..||.. |..||.||.......:||...|.|..:.|..   |||:||:..:|::|:.
Zfish    18 SGSLCQL-DVCGRAPLKPRIIGGQTAMAGSWPWQVSIHYIPTGGLL---CGGTLINREWVLSAAQ 78

  Fly   174 CVNGKALPTDWRLSG----VRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPAS 234
            |..        :|:.    |.||...|..               |..:..|..:.|.||.|..|:
Zfish    79 CFQ--------KLTASNLVVHLGHLSTGD---------------PNVIHNPASQIINHPKYDSAT 120

  Fly   235 KNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTE------QLSASNL 293
            ..  ||||||:|:..|.:||:::|:||...   .|:...|....:.|||...      ..:...:
Zfish   121 NK--NDIALLKLSTPVSFTDYIKPVCLTAS---GSSLGKGAVSWITGWGSINTGGTQFPTTLQEV 180

  Fly   294 KLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDS-CRGDSGGPLIGLDTNKVNTYYFLA 357
            |:.....|    :|::.|.|   |:.|..:|||..||... |.||.||||:    :..:..:..:
Zfish   181 KIPVVSNG----DCKSAYGS---LITDGMICAGPNEGGKGICMGDGGGPLV----HNSSEQWIQS 234

  Fly   358 GVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            |:.||| ..|.....|||:|.|.:|..||::.|
Zfish   235 GIASFG-RGCAQPKNPGVFTRVSEYESWIKSQI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	77/269 (29%)
		Tryp_SPc	128..389	CDD:238113	78/271 (29%)
zgc:153968	NP_001070924.1	Tryp_SPc	35..262	CDD:214473	77/269 (29%)
zgc:153968	NP_001070924.1	Tryp_SPc	36..265	CDD:238113	78/271 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587394
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840