DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Prss8

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_579929.1	Gene:	Prss8 / 76560	MGIID:	1923810	Length:	339	Species:	Mus musculus

Alignment Length:	290	Identity:	91/290 - (31%)
Similarity:	139/290 - (47%)	Gaps:	60/290 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 CGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHH-CGGSLISTRYVITASHCVNGKALPTD 183
            ||.::..||.||...|..::||...|.|      .|:| |||||:|.::|::|:||     .|.:
Mouse    37 CGAVIQPRITGGGSAKPGQWPWQVSITY------DGNHVCGGSLVSNKWVVSAAHC-----FPRE 90

  Fly   184 WRLSG--VRLG--EWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALL 244
            .....  |:||  :.|:.:| |..|..              |.:.|.|..|  ..:....||||:
Mouse    91 HSREAYEVKLGAHQLDSYSN-DTVVHT--------------VAQIITHSSY--REEGSQGDIALI 138

  Fly   245 RLAQQVEYTDFVRPICLPLDVNLRSATF-DGITMDVAGWGKTEQLSASNLKLKA-------AVEG 301
            ||:..|.::.::||||||    ..:|:| :|:...|.|||..    |.::.|:.       .|..
Mouse   139 RLSSPVTFSRYIRPICLP----AANASFPNGLHCTVTGWGHV----APSVSLQTPRPLQQLEVPL 195

  Fly   302 FRMDECQNVYSSQDI-----LLEDTQMCAG-GKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAGVV 360
            ...:.|..:|:...:     .::...:||| .|.|.|:|:|||||||    :..:...::|||:|
Mouse   196 ISRETCSCLYNINAVPEEPHTIQQDMLCAGYVKGGKDACQGDSGGPL----SCPMEGIWYLAGIV 256

  Fly   361 SFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            |:|.. ||....||||||...|..||.:.:
Mouse   257 SWGDA-CGAPNRPGVYTLTSTYASWIHHHV 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	87/277 (31%)
		Tryp_SPc	128..389	CDD:238113	88/279 (32%)
Prss8	NP_579929.1	Tryp_SPc	45..284	CDD:238113	88/279 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910