DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG18735

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	105/301 - (34%)
Similarity:	149/301 - (49%)	Gaps:	47/301 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 ESSSETTPPPKPNVTSNSLLPLPGQCGNI-LSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHC 158
            |..:|.:.|.|......|       |||| ..:||.||.:|::.|:|||.::.:..:     .:|
  Fly    56 EVPAEWSSPAKRECAECS-------CGNINTRHRIVGGQETEVHEYPWMIMLMWFGN-----FYC 108

  Fly   159 GGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVER 223
            |.||::.:|.:||:|||||    ...||..|||.|   :...|..|.:          :|..|.|
  Fly   109 GASLVNDQYALTAAHCVNG----FYHRLITVRLLE---HNRQDSHVKI----------VDRRVSR 156

  Fly   224 TIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGK-TEQ 287
            .:.||.|  :::|..:||||:|..:.|.....:.|:|:|..    |..:.|.|..|.|||. :|.
  Fly   157 VLIHPKY--STRNFDSDIALIRFNEPVRLGIDMHPVCMPTP----SENYAGQTAVVTGWGALSEG 215

  Fly   288 LSASNLKLKAAVEGFRMDECQNV-YSSQDILLEDTQMCAGGKE--GVDSCRGDSGGPLIGLDTNK 349
            ...|:...:..|.....:||:|. |....|  .|..:|||..|  |.|||:||||||:..|.:..
  Fly   216 GPISDTLQEVEVPILSQEECRNSNYGESKI--TDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGD 278

  Fly   350 VNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI-QNT 389
            .   |.|||:||:| ..|.....|||||.||.:.||| :||
  Fly   279 A---YQLAGIVSWG-EGCAKPNAPGVYTRVGSFNDWIAENT 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	92/262 (35%)
		Tryp_SPc	128..389	CDD:238113	93/265 (35%)
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	92/262 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	93/264 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457525
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	4	3.940