DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ea and prss27

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	104/301 - (34%)
Similarity:	149/301 - (49%)	Gaps:	65/301 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LLPLPG---------QCG-NILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRY 167
            ||..||         .|| .::|:||.||...:..::||....   ::.|  ||.|||:|||.:|
Frog     9 LLLTPGLLGITPGATDCGIPLVSSRIMGGQSAQEGQWPWQVSF---RNNG--GHFCGGTLISKQY 68

  Fly   168 VITASHCVNGKALPTDWRLSGVR--LGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDY 230
            ||:|:||     .|:....|.|.  ||.:..: .||..            .:.:||:....:|.|
Frog    69 VISAAHC-----FPSSSSASSVTAVLGAYMID-QPDGN------------QVAIPVQSATNYPSY 115

  Fly   231 IPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATF-DGITMDVAGWGKTEQLSASNLK 294
            :  ::....||:|::||..|.:|:::.|:|||.|    :.|| .|:...|.|||..    ||::.
Frog   116 V--NEGDSGDISLVQLASPVTFTNYILPVCLPAD----TVTFPTGLQCWVTGWGNI----ASDVS 170

  Fly   295 L-------KAAVEGFRMDECQ------NVYSSQDILLEDTQMCAGG-KEGVDSCRGDSGGPLIGL 345
            |       :.||.....:||.      |.|.:..|.:....:|||. ..|.|||:|||||||:..
Frog   171 LVSPMTLQEVAVPLIDANECNALYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCS 235

  Fly   346 DTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI 386
            .:.:    :||||||||| ..||.|..||||||:..|.|||
Frog   236 SSGQ----WFLAGVVSFG-EGCGQAYRPGVYTLMPSYTDWI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	95/275 (35%)
		Tryp_SPc	128..389	CDD:238113	96/276 (35%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	94/274 (34%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910