DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and zgc:92313

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001002596.1	Gene:	zgc:92313 / 436869	ZFINID:	ZDB-GENE-040718-339	Length:	309	Species:	Danio rerio

Alignment Length:	300	Identity:	91/300 - (30%)
Similarity:	135/300 - (45%)	Gaps:	77/300 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 QCGN-ILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHH-CGGSLISTRYVITASHCVNGKALP 181
            :||. .:.|||.||.......:||...|     ||:|..| |||::||..:|::|:||...   |
Zfish    25 ECGRPPMINRIVGGSSAADGAWPWQVDI-----QGEKSKHVCGGTIISENWVLSAAHCFPN---P 81

  Fly   182 TDWRLSGV-------RLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVN 239
            .|  :||.       :|..|    ||| |...|             :.|.:....|......|
Zfish    82 ND--ISGYLIYAGRQQLNGW----NPD-ETSHR-------------ISRVVVPLGYTDPQLGQ-- 124

  Fly   240 DIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMD----VAGWGKTEQLSASNLKLKAAVE 300
            ||||:.||....||:.::|:|||. .|:.      .|.|    :.|||        :::...|::
Zfish   125 DIALVELATPFVYTERIQPVCLPY-ANVE------FTSDMRCMITGWG--------DIREGVALQ 174

  Fly   301 GFR---------MDE--CQNVY---SSQDILLEDTQMCAGGKE-GVDSCRGDSGGPLIGLDTNKV 350
            |..         :|.  ||:::   .:::|.:....||||.:: |.|||:|||||||.   ....
Zfish   175 GVGPLQEVQVPIIDSQICQDMFLTNPTENIDIRPDMMCAGFQQGGKDSCQGDSGGPLA---CQIS 236

  Fly   351 NTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            :..:..||:|||| ..|..|..||||..|..:.::||..:
Zfish   237 DGSWVQAGIVSFG-LGCAEANRPGVYAKVSSFTNFIQTHV 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	86/285 (30%)
		Tryp_SPc	128..389	CDD:238113	87/287 (30%)
zgc:92313	NP_001002596.1	Tryp_SPc	34..271	CDD:214473	86/285 (30%)
zgc:92313	NP_001002596.1	Tryp_SPc	35..274	CDD:238113	87/287 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840